Details

SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGHV1-3*i01
IUIS Name
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityF
Inference TypeRearranged Only
Mapped
Paralogs
Paralog Rep

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

No Items

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start
CDR1 End
CDR2 Start
CDR2 End
CDR3 Start

Non-Core Regions

Exon 1 Start
Exon 1 End
Exon 2 Start
Exon 2 End
Exon 3 Start
Exon 3 End
Exon 4 Start
Exon 4 End
Exon 5 Start
Exon 5 End
Exon 6 Start
Exon 6 End
Exon 7 Start
Exon 7 End
Exon 8 Start
Exon 8 End
Exon 9 Start
Exon 9 End
UTR 3' Start
UTR 3' End

Additional Information

Sequence IDA00007
Curator
Curator addressSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney Australia
Version2
Release Date2019-04-12
Release Notes
LocusIGH
Sequence TypeV
Gene Subgroup1
Gene Designation3
Allele Designationi01
Gene start
Gene end

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Originally approved by IARC on March 9, 2018.

“The sequence was inferred [..] using IgDiscover, and [..] using both Partis and TIgGER. The number of unique CDR3 used by sequences with exact matches to the inferred germline allele represents 1.3% of all unique CDR3 [unmutated frequency: 1.17%] associated to exact IGHV matches in the genotype, according to IgDiscover. There were at least 775 unique rearrangements, utilizing 22 D genes and 7 J genes. The allele was the more frequently utilized allele, with an expression ratio of 56:44 with the *01 allele. The inference was supported by haplotype analysis using IGHJ6*02/*03.”

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

Mats Ohlin
2018-12-21 12:09:07
Version 1 published

Submission published by IARC on Dec 21, 2018.

Mats Ohlin
2019-04-12 14:30:09
Version 2 published

Version 2 published

Changes from previous version

v1v2
Full Sequence
Coding Sequence

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGHV1-3*i0112018-12-21
IGHV1-3*i0122019-04-12
IGHV1-3*i0132019-04-12
IGHV1-3*i0142019-04-12
IGHV1-3*i01IGHV1-3*0452019-05-16
IGHV1-3*04IGHV1-3*0462023-07-10