Sequence IGHV1-3*i01
Details
| Species | Human |
| Species subgroup | |
| Subgroup type | |
| Sequence Name | IGHV1-3*i01 |
| IUIS Name | |
| Alternative names | |
| Affirmation Level | 1 |
| Full Sequence | |
| Coding Sequence | |
| Functionality | F |
| Inference Type | Rearranged Only |
| Mapped | |
| Paralogs | |
| Paralog Rep |
Un-rearranged Observations
Un-rearranged sequence observations that support this sequence:
Observations in AIRR-seq Repertoires
Click here to review supporting data in VDJbase.
Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.
CDR delineation
| CDR1 Start | |
| CDR1 End | |
| CDR2 Start | |
| CDR2 End | |
| CDR3 Start |
Additional Information
| Sequence ID | A00007 |
| Curator | |
| Curator address | School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney Australia |
| Version | 4 |
| Release Date | 2019-04-12 |
| Release Notes | A trailing “.” in the sequence indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation. |
| Locus | IGH |
| Sequence Type | V |
| Gene Subgroup | 1 |
| Gene Designation | 3 |
| Allele Designation | i01 |
Notes
Notes are added by IARC reviewers.
| Originally approved by IARC on March 9, 2018. “The sequence was inferred [..] using IgDiscover, and [..] using both Partis and TIgGER. The number of unique CDR3 used by sequences with exact matches to the inferred germline allele represents 1.3% of all unique CDR3 [unmutated frequency: 1.17%] associated to exact IGHV matches in the genotype, according to IgDiscover. There were at least 775 unique rearrangements, utilizing 22 D genes and 7 J genes. The allele was the more frequently utilized allele, with an expression ratio of 56:44 with the *01 allele. The inference was supported by haplotype analysis using IGHJ6*02/*03.” (April 12, 2019) A trailing “.” in the sequence indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation. |
Attachments
History
History logs the times and reasons for the publication of each version of this sequence.
| Mats Ohlin 2018-12-21 12:09:07 | Version 1 published Submission published by IARC on Dec 21, 2018. |
| Mats Ohlin 2019-04-12 14:30:09 | Version 2 published Version 2 published |
| Mats Ohlin 2019-04-12 14:31:16 | Version 3 published In line with IARC policy, the submitted sequence was recognized up to and including nucleotide 319. A trailing “.” indicates IARC’s opinion that the sequences likely to contain an additional/additional 3’ nucleotide(s) for which there is insufficient evidence to make an affirmation. |
| Mats Ohlin 2019-04-12 14:52:06 | Version 4 published A trailing “.” in the sequence indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation. |
Changes from previous version
| v3 | v4 | |
|---|---|---|
| Notes | changed |
Versions
All published versions of this sequence.
| Sequence Name | IMGT Name | Alternative names | Inference Type | Affirmation Level | Species subgroup | Subgroup type | Gene start | Gene end | UTR 5' Start | UTR 5' End | L-PART1 Start | L-PART1 End | L-PART2 Start | L-PART2 End | CDR1 Start | CDR1 End | CDR2 Start | CDR2 End | CDR3 Start | v_rs_start | v_rs_end | d_rs_3_prime_start | d_rs_3_prime_end | d_rs_5_prime_start | d_rs_5_prime_end | j_rs_start | j_rs_end | Codon Frame | Version | Date |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IGHV1-3*i01 | Rearranged Only | 1 | 1 | 2018-12-21 | ||||||||||||||||||||||||||
| IGHV1-3*i01 | Rearranged Only | 1 | 2 | 2019-04-12 | ||||||||||||||||||||||||||
| IGHV1-3*i01 | Rearranged Only | 1 | 3 | 2019-04-12 | ||||||||||||||||||||||||||
| IGHV1-3*i01 | Rearranged Only | 1 | 4 | 2019-04-12 | ||||||||||||||||||||||||||
| IGHV1-3*i01 | IGHV1-3*04 | Rearranged Only | 1 | 5 | 2019-05-16 | |||||||||||||||||||||||||
| IGHV1-3*04 | IGHV1-3*04 | IGHV1-3*i01 | Rearranged Only | 1 | 1 | 295 | 76 | 99 | 151 | 174 | 289 | 6 | 2023-07-10 |