Species subgroup
Subgroup type
Sequence NameIGHV5-51*i01
IUIS NameIGHV5-51*06
Alternative namesIGHV5-51*p13
Affirmation Level1
Full Sequence
Coding Sequence
Inference TypeRearranged Only
Alternative namesIGHV5-51*p13


The table below lists the submissions, and the inferences within them, on which this published sequence is based. The list may be short when the sequence is first published, containing, for example, reference to just a single submission, but is expected to grow over time as additional inferences are submitted.

'Sequence Match' indicates whether the inference exactly matches the sequence, and clicking on the tick or cross will provide an alignment. Mismatches may be caused, for example, by the inclusion of leader sequences, or nucleotides in the inference which do not in IARC's opinion have sufficient evidence for inclusion in the sequence.

Submission IDAccession NoSubject IDGenotype NameSequence NameSequence Match
S00007 MK321694LP08248LP08248IGHV5-51*03+C203T

Supporting Observations

Sequences in other published genotypes which have been identified by IARC and support the inference:

No Items

Observations in VDJbase

Inferred sequences in VDJbase that match this sequence:

No Items

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

No Items

Additional Information

Sequence IDA00013
Curator addressDept. of Immunotechnology, Lund University, Medicon Village building 406, S-22381 Lund, Sweden
Release Date2019-05-16
Release Notes

IMGT allele name added

Sequence TypeV
Gene Subgroup5
Gene Designation51
Allele Designationi01


Individuals acknowledged as contributing to this sequence:

No Items


Notes are added by IARC reviewers.

This sequence represents IGHV5-51*03 C228T in the IMGT numbering system. The committee noted a rearrangement frequency of 1.25%, with 1128 alignments including 304 perfect matches to the inferred allele. There was abundant variation in the CDR3 regions of the aligned sequences. The genotype showed the individual to be heterozygous at the IGHV5-51 locus, with the alternative IGHV5-51*03 allele being associated with 1539 sequences for an allele ratio of 42:58. The sequence was affirmed at level 1 at IARC Meeting 33 on March 15, 2019. The sequence is affirmed only up to and including base 318, the final base of the inference and its GenBank record, and of the corresponding closest allele (IGHV5-51*03) in the IMGT database.

(April 12, 2019) A trailing “.” indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.


No Items


History logs the times and reasons for the publication of each version of this sequence.

Andrew Collins
2019-04-02 22:39:35
Version 1 published

Submission published by IARC on April 3, 2019

Mats Ohlin
2019-04-12 14:47:01
Version 2 published

A trailing “.” indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.

Mats Ohlin
2019-05-16 21:56:33
Version 3 published

IMGT allele name added

Changes from previous version

IUIS NameIGHV5-51*06


All published versions of this sequence.

Sequence NameIMGT NameAlternative namesInference TypeAffirmation LevelSpecies subgroupSubgroup typeVersionDate
IGHV5-51*i01IGHV5-51*p13Rearranged Only112019-04-02
IGHV5-51*i01IGHV5-51*p13Rearranged Only122019-04-12
IGHV5-51*i01IGHV5-51*06IGHV5-51*p13Rearranged Only132019-05-16