Sequence IGHV5-51*i01
Details
| Species | Human |
| Species subgroup | |
| Subgroup type | |
| Sequence Name | IGHV5-51*i01 |
| IUIS Name | |
| Alternative names | IGHV5-51*p13 |
| Affirmation Level | 1 |
| Full Sequence | |
| Coding Sequence | |
| Functionality | F |
| Inference Type | Rearranged Only |
| Alternative names | IGHV5-51*p13 |
| Paralogs |
Evidence
The table below lists the submissions, and the inferences within them, on which this published sequence is based. The list may be short when the sequence is first published, containing, for example, reference to just a single submission, but is expected to grow over time as additional inferences are submitted.
'Sequence Match' indicates whether the inference exactly matches the sequence, and clicking on the tick or cross will provide an alignment. Mismatches may be caused, for example, by the inclusion of leader sequences, or nucleotides in the inference which do not in IARC's opinion have sufficient evidence for inclusion in the sequence.
| Submission ID | Accession No | Subject ID | Genotype Name | Sequence Name | Sequence Match |
|---|---|---|---|---|---|
| S00007 | MK321694 | LP08248 | LP08248 | IGHV5-51*03+C203T |
Supporting Observations
Sequences in other published genotypes which have been identified by IARC and support the inference:
Observations in VDJbase
Inferred sequences in VDJbase that match this sequence:
Un-rearranged Observations
Un-rearranged sequence observations that support this sequence:
Additional Information
| Sequence ID | A00013 |
| Curator address | Dept. of Immunotechnology, Lund University, Medicon Village building 406, S-22381 Lund, Sweden |
| Version | 2 |
| Release Date | 2019-04-12 |
| Release Notes | A trailing “.” indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation. |
| Locus | IGH |
| Sequence Type | V |
| Gene Subgroup | 5 |
| Gene Designation | 51 |
| Allele Designation | i01 |
Notes
Notes are added by IARC reviewers.
| This sequence represents IGHV5-51*03 C228T in the IMGT numbering system. The committee noted a rearrangement frequency of 1.25%, with 1128 alignments including 304 perfect matches to the inferred allele. There was abundant variation in the CDR3 regions of the aligned sequences. The genotype showed the individual to be heterozygous at the IGHV5-51 locus, with the alternative IGHV5-51*03 allele being associated with 1539 sequences for an allele ratio of 42:58. The sequence was affirmed at level 1 at IARC Meeting 33 on March 15, 2019. The sequence is affirmed only up to and including base 318, the final base of the inference and its GenBank record, and of the corresponding closest allele (IGHV5-51*03) in the IMGT database. (April 12, 2019) A trailing “.” indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation. |
Attachments
History
History logs the times and reasons for the publication of each version of this sequence.
| Andrew Collins 2019-04-02 22:39:35 | Version 1 published Submission published by IARC on April 3, 2019 |
| Mats Ohlin 2019-04-12 14:47:01 | Version 2 published A trailing “.” indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation. |
Changes from previous version
| v1 | v2 | |
|---|---|---|
| Notes | changed |
Versions
All published versions of this sequence.
| Sequence Name | IMGT Name | Alternative names | Inference Type | Affirmation Level | Species subgroup | Subgroup type | Version | Date |
|---|---|---|---|---|---|---|---|---|
| IGHV5-51*i01 | IGHV5-51*p13 | Rearranged Only | 1 | 1 | 2019-04-02 | |||
| IGHV5-51*i01 | IGHV5-51*p13 | Rearranged Only | 1 | 2 | 2019-04-12 | |||
| IGHV5-51*i01 | IGHV5-51*06 | IGHV5-51*p13 | Rearranged Only | 1 | 3 | 2019-05-16 |