Details

SpeciesHuman
Species subgroup
Subgroup type
Sequence NameIGHV5-51*i01
IUIS Name
Alternative namesIGHV5-51*p13
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityF
Inference TypeRearranged Only
Mapped
Paralogs
Paralog Rep

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

No Items

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

Additional Information

Sequence IDA00013
Curator
Curator addressDept. of Immunotechnology, Lund University, Medicon Village building 406, S-22381 Lund, Sweden
Version2
Release Date2019-04-12
Release Notes

A trailing “.” indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.

LocusIGH
Sequence TypeV
Gene Subgroup5
Gene Designation51
Allele Designationi01

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

This sequence represents IGHV5-51*03 C228T in the IMGT numbering system. The committee noted a rearrangement frequency of 1.25%, with 1128 alignments including 304 perfect matches to the inferred allele. There was abundant variation in the CDR3 regions of the aligned sequences. The genotype showed the individual to be heterozygous at the IGHV5-51 locus, with the alternative IGHV5-51*03 allele being associated with 1539 sequences for an allele ratio of 42:58. The sequence was affirmed at level 1 at IARC Meeting 33 on March 15, 2019. The sequence is affirmed only up to and including base 318, the final base of the inference and its GenBank record, and of the corresponding closest allele (IGHV5-51*03) in the IMGT database.

(April 12, 2019) A trailing “.” indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

Andrew Collins
2019-04-02 22:39:35
Version 1 published

Submission published by IARC on April 3, 2019

Mats Ohlin
2019-04-12 14:47:01
Version 2 published

A trailing “.” indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.

Changes from previous version

v1v2
Noteschanged

Versions

All published versions of this sequence.

Sequence NameIMGT NameAlternative namesInference TypeAffirmation LevelSpecies subgroupSubgroup typeVersionDate
IGHV5-51*i01IGHV5-51*p13Rearranged Only112019-04-02
IGHV5-51*i01IGHV5-51*p13Rearranged Only122019-04-12
IGHV5-51*i01IGHV5-51*06IGHV5-51*p13Rearranged Only132019-05-16
IGHV5-51*06IGHV5-51*06IGHV5-51*i01Unrearranged and Rearranged1none52023-07-24
IGHV5-51*06IGHV5-51*06IGHV5-51*i01Genomic Only1none62023-08-16