Species subgroup
Subgroup type
Sequence NameIGLV3-25*i01
IUIS NameIGLV3-25*03
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
Inference TypeRearranged Only
Alternative names


The table below lists the submissions, and the inferences within them, on which this published sequence is based. The list may be short when the sequence is first published, containing, for example, reference to just a single submission, but is expected to grow over time as additional inferences are submitted.

'Sequence Match' indicates whether the inference exactly matches the sequence, and clicking on the tick or cross will provide an alignment. Mismatches may be caused, for example, by the inclusion of leader sequences, or nucleotides in the inference which do not in IARC's opinion have sufficient evidence for inclusion in the sequence.

Submission IDAccession NoSubject IDGenotype NameSequence NameSequence Match
S00028 MK308865A007A007 VLIGLV3-25*02_S7225

Supporting Observations

Sequences in other published genotypes which have been identified by IARC and support the inference:

No Items

Observations in VDJbase

Inferred sequences in VDJbase that match this sequence:

No Items

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

No Items

Additional Information

Sequence IDA00057
Curator addressSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney Australia
Release Date2020-08-10
Release Notes

Correct sequence name from *01 to *i01

Sequence TypeV
Gene Subgroup3
Gene Designation25
Allele Designationi01


Individuals acknowledged as contributing to this sequence:

No Items


Notes are added by IARC reviewers.

This sequence was first affirmed at the IARC Meeting 57 on July 7th 2020, where it was noted:

“The sequence was seen in 4.53% of all unmutated rearrangements, with 16,227 sequences including 5410 perfect alignments to the inferred allele. There was abundant variation in the CDR3 regions of the aligned sequences. A second IGLV3-25 allele, IGLV3-25*02, was also present in the genotype, at a lower frequency, and the inferred allele accounted for 73% of all IGLV3-25 alignments. Haplotype data is unavailable. Plots of the final 3’ nucleotides were considered, but the variability seen made it impossible to consider the final two nucleotides of the sequence. These were not part of the Genbank submission. The sequence has previously been reported as IGLV3-25*p04. The sequence, up to and including nucleotide 339, was affirmed as the Level 1 sequence, IGLV3-25*i01. It appears to represent the full length version of the previously truncated IGLV3-25*03 sequence. It was subsequently noted that since the submission of this sequence, an identical genomic sequence has been accepted by IMGT as the full length sequence IGLV3-25*03. The sequence, up to and including nucleotide 339 will be submitted to IMGT as IGLV3-25*i01 as a record of the rearrangability (and therefore likely functionality) of the sequence. “


Supplementary Files


History logs the times and reasons for the publication of each version of this sequence.

Andrew Collins
2020-08-01 13:22:28
Version 1 published

Published by the IARC on 1/8/2020.

William Lees
2020-08-10 15:53:51
Version 2 published

Correct sequence name from *01 to *i01

Changes from previous version

Sequence NameIGLV3-25*01IGLV3-25*i01


All published versions of this sequence.

Sequence NameIMGT NameAlternative namesInference TypeAffirmation LevelSpecies subgroupSubgroup typeVersionDate
IGLV3-25*01IGLV3-25*03Rearranged Only112020-08-01
IGLV3-25*i01IGLV3-25*03Rearranged Only122020-08-10