|Inference Type||Rearranged Only|
The table below lists the submissions, and the inferences within them, on which this published sequence is based. The list may be short when the sequence is first published, containing, for example, reference to just a single submission, but is expected to grow over time as additional inferences are submitted.
'Sequence Match' indicates whether the inference exactly matches the sequence, and clicking on the tick or cross will provide an alignment. Mismatches may be caused, for example, by the inclusion of leader sequences, or nucleotides in the inference which do not in IARC's opinion have sufficient evidence for inclusion in the sequence.
Sequences in other published genotypes which have been identified by IARC and support the inference:
Inferred sequences in VDJbase that match this sequence:
Un-rearranged sequence observations that support this sequence:
|Curator address||School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney Australia|
|Release Notes|| |
IMGT allele name added
Notes are added by IARC reviewers.
Originally approved by IARC on April 13, 2018.
“The sequence is present at high frequency (1.3%), in the IgDiscover analysis. It was inferred by IgDiscover, TIger and Partis. Haplotype analysis was supportive of the inference, as the sequence was strongly associated with the IGHJ6*03 haplotype. The sequence has previously been reported from genomic sequencing, and by inference from VDJ data, and is documented in IgPdb as IGHV4-30-4*p08. It was agreed that the sequence should be moved to Level 1.”
In line with IARC policy, the submitted sequence was recognized up to and including nucleotide 319.
(April 12, 2019) A trailing “.” in the sequence indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.
History logs the times and reasons for the publication of each version of this sequence.
|Version 1 published|
Submission published by IARC on Dec 21, 2018.
|Version 2 published|
This version was created to include details highlighting the fact that the published sequence was affirmed up to and including nucleotide 319, but the submitted sequence was one nucleotide longer.
|Version 3 published|
A trailing “.” in the sequence indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.
|Version 4 published|
IMGT allele name added