Species subgroup
Subgroup type
Sequence NameIGHV4-30-4*i01
IUIS NameIGHV4-30-4*08
Alternative namesIGHV4-30-4*p08
Affirmation Level1
Full Sequence
Coding Sequence
Inference TypeRearranged Only
Alternative namesIGHV4-30-4*p08


The table below lists the submissions, and the inferences within them, on which this published sequence is based. The list may be short when the sequence is first published, containing, for example, reference to just a single submission, but is expected to grow over time as additional inferences are submitted.

'Sequence Match' indicates whether the inference exactly matches the sequence, and clicking on the tick or cross will provide an alignment. Mismatches may be caused, for example, by the inclusion of leader sequences, or nucleotides in the inference which do not in IARC's opinion have sufficient evidence for inclusion in the sequence.

Submission IDAccession NoSubject IDGenotype NameSequence NameSequence Match
S00006 MH779624B16B16IGHV4-30-4*01_S4754

Supporting Observations

Sequences in other published genotypes which have been identified by IARC and support the inference:

No Items

Observations in VDJbase

Inferred sequences in VDJbase that match this sequence:

No Items

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

No Items

Additional Information

Sequence IDA00009
Curator addressSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney Australia
Release Date2019-05-16
Release Notes

IMGT allele name added

Sequence TypeV
Gene Subgroup4
Gene Designation30-4
Allele Designationi01


Individuals acknowledged as contributing to this sequence:

No Items


Notes are added by IARC reviewers.

Originally approved by IARC on April 13, 2018.

“The sequence is present at high frequency (1.3%), in the IgDiscover analysis. It was inferred by IgDiscover, TIger and Partis. Haplotype analysis was supportive of the inference, as the sequence was strongly associated with the IGHJ6*03 haplotype. The sequence has previously been reported from genomic sequencing, and by inference from VDJ data, and is documented in IgPdb as IGHV4-30-4*p08. It was agreed that the sequence should be moved to Level 1.”

In line with IARC policy, the submitted sequence was recognized up to and including nucleotide 319.

(April 12, 2019) A trailing “.” in the sequence indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.


No Items


History logs the times and reasons for the publication of each version of this sequence.

Mats Ohlin
2018-12-21 12:11:12
Version 1 published

Submission published by IARC on Dec 21, 2018.

Andrew Collins
2019-04-03 04:21:41
Version 2 published

This version was created to include details highlighting the fact that the published sequence was affirmed up to and including nucleotide 319, but the submitted sequence was one nucleotide longer.

Mats Ohlin
2019-04-12 14:51:13
Version 3 published

A trailing “.” in the sequence indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.

Mats Ohlin
2019-05-16 21:50:41
Version 4 published

IMGT allele name added

Changes from previous version

IUIS NameIGHV4-30-4*08


All published versions of this sequence.

Sequence NameIMGT NameAlternative namesInference TypeAffirmation LevelSpecies subgroupSubgroup typeVersionDate
IGHV4-30-4*i01IGHV4-30-4*p08Rearranged Only112018-12-21
IGHV4-30-4*i01IGHV4-30-4*p08Rearranged Only122019-04-03
IGHV4-30-4*i01IGHV4-30-4*p08Rearranged Only132019-04-12
IGHV4-30-4*i01IGHV4-30-4*08IGHV4-30-4*p08Rearranged Only142019-05-16