Details

SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGHV4-30-4*i01
IUIS NameIGHV4-30-4*08
Alternative namesIGHV4-30-4*p08
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityF
Inference TypeRearranged Only
Mapped
Paralogs
Paralog Rep

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

No Items

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start
CDR1 End
CDR2 Start
CDR2 End
CDR3 Start

Additional Information

Sequence IDA00009
Curator
Curator addressSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney Australia
Version4
Release Date2019-05-16
Release Notes

IMGT allele name added

LocusIGH
Sequence TypeV
Gene Subgroup4
Gene Designation30-4
Allele Designationi01
Gene start
Gene end

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Originally approved by IARC on April 13, 2018.

“The sequence is present at high frequency (1.3%), in the IgDiscover analysis. It was inferred by IgDiscover, TIger and Partis. Haplotype analysis was supportive of the inference, as the sequence was strongly associated with the IGHJ6*03 haplotype. The sequence has previously been reported from genomic sequencing, and by inference from VDJ data, and is documented in IgPdb as IGHV4-30-4*p08. It was agreed that the sequence should be moved to Level 1.”

In line with IARC policy, the submitted sequence was recognized up to and including nucleotide 319.

(April 12, 2019) A trailing “.” in the sequence indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

Mats Ohlin
2018-12-21 12:11:12
Version 1 published

Submission published by IARC on Dec 21, 2018.

Andrew Collins
2019-04-03 04:21:41
Version 2 published

This version was created to include details highlighting the fact that the published sequence was affirmed up to and including nucleotide 319, but the submitted sequence was one nucleotide longer.

Mats Ohlin
2019-04-12 14:51:13
Version 3 published

A trailing “.” in the sequence indicates IARC’s opinion that the sequence is likely to contain additional 3’ nucleotides for which there is insufficient evidence to make an affirmation.

Mats Ohlin
2019-05-16 21:50:41
Version 4 published

IMGT allele name added

Changes from previous version

v3v4
IUIS NameIGHV4-30-4*08

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGHV4-30-4*i0112018-12-21
IGHV4-30-4*i0122019-04-03
IGHV4-30-4*i0132019-04-12
IGHV4-30-4*i01IGHV4-30-4*0842019-05-16
IGHV4-30-4*08IGHV4-30-4*0852023-07-10