Species subgroup
Subgroup type
Sequence NameIGHV1-58*i01
IUIS NameIGHV1-58*03
Alternative namesIGHV1-58*p04
Affirmation Level1
Full Sequence
Coding Sequence
Inference TypeRearranged Only
Alternative namesIGHV1-58*p04


The table below lists the submissions, and the inferences within them, on which this published sequence is based. The list may be short when the sequence is first published, containing, for example, reference to just a single submission, but is expected to grow over time as additional inferences are submitted.

'Sequence Match' indicates whether the inference exactly matches the sequence, and clicking on the tick or cross will provide an alignment. Mismatches may be caused, for example, by the inclusion of leader sequences, or nucleotides in the inference which do not in IARC's opinion have sufficient evidence for inclusion in the sequence.

Submission IDAccession NoSubject IDGenotype NameSequence NameSequence Match
S00008 MK321684LP23810LP23810IGHV1-58*01+G29A

Supporting Observations

Sequences in other published genotypes which have been identified by IARC and support the inference:

No Items

Observations in VDJbase

Inferred sequences in VDJbase that match this sequence:

No Items

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

No Items

Additional Information

Sequence IDA00014
Curator addressDept. of Immunotechnology, Lund University, Medicon Village building 406, S-22381 Lund, Sweden
Release Date2019-05-16
Release Notes

IMGT allele name added

Sequence TypeV
Gene Subgroup1
Gene Designation58
Allele Designationi01


Individuals acknowledged as contributing to this sequence:

No Items


Notes are added by IARC reviewers.

This sequence represents IGHV1-58*01+G33A in the IMGT numbering system. The committee noted a rearrangement frequency of 0.15%, with 178 alignments including 127 perfect matches to the inferred allele. There was abundant variation in the CDR3 regions of the aligned sequences. The genotype showed the individual to be heterozygous at the IGHV1-58 locus, with the alternative IGHV1-58*01 allele being associated with 214 sequences for an allele ratio of 45:55. This sequence has previously been catalogued by IgPdb as IGHV1-58*p04, though the IgPdb sequence is derived from the S0008 dataset. All members of the committee agreed that the sequence should be accepted as a Level 1 sequence at IARC Meeting 34 on March 29, 2019. In line with previous policy, the submitted sequence will be recognized up to and including nucleotide 319. A trailing “.” indicates IARC’s opinion that the sequences likely to contain an additional/additional 3’ nucleotide(s) for which there is insufficient evidence to make an affirmation.


No Items


History logs the times and reasons for the publication of each version of this sequence.

Mats Ohlin
2019-04-12 14:38:50
Version 1 published

Accepted as a Level 1 sequence at IARC Meeting 34 on March 29, 2019.

Mats Ohlin
2019-05-16 21:48:45
Version 2 published

IMGT allele name added

Changes from previous version

IUIS NameIGHV1-58*03


All published versions of this sequence.

Sequence NameIMGT NameAlternative namesInference TypeAffirmation LevelSpecies subgroupSubgroup typeVersionDate
IGHV1-58*i01IGHV1-58*p04Rearranged Only112019-04-12
IGHV1-58*i01IGHV1-58*03IGHV1-58*p04Rearranged Only122019-05-16