SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGHV1-58*03
IUIS NameIGHV1-58*03
Alternative namesIGHV1-58*i01
Affirmation Level1
Full Sequence
Coding Sequence
Inference TypeRearranged Only
Paralog RepFalse

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:


Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start76
CDR1 End99
CDR2 Start151
CDR2 End174
CDR3 Start289


3' ExtensionA
3' start
3' end

Additional Information

Sequence IDA00014
CuratorWilliam Lees
Curator addressBirkbeck College, University of London, Malet Street, London
Release Date2023-07-10
Release Notes

Bulk upload of sequences for the AIRR-C Human IG germline sets

Sequence TypeV
Gene Subgroup1
Gene Designation58
Allele Designation03


Individuals acknowledged as contributing to this sequence:

No Items


Notes are added by IARC reviewers.

This sequence represents IGHV1-58*01+G33A in the IMGT numbering system. The committee noted a rearrangement frequency of 0.15%, with 178 alignments including 127 perfect matches to the inferred allele. There was abundant variation in the CDR3 regions of the aligned sequences. The genotype showed the individual to be heterozygous at the IGHV1-58 locus, with the alternative IGHV1-58*01 allele being associated with 214 sequences for an allele ratio of 45:55. This sequence has previously been catalogued by IgPdb as IGHV1-58*p04, though the IgPdb sequence is derived from the S0008 dataset. All members of the committee agreed that the sequence should be accepted as a Level 1 sequence at IARC Meeting 34 on March 29, 2019. In line with previous policy, the submitted sequence will be recognized up to and including nucleotide 319. A trailing “.” indicates IARC’s opinion that the sequences likely to contain an additional/additional 3’ nucleotide(s) for which there is insufficient evidence to make an affirmation.

Additional information for this sequence was imported into OGRDB via bulk update with the following notes:
Sequence annotation is based on Genbank sample MK321684


No Items


History logs the times and reasons for the publication of each version of this sequence.

Mats Ohlin
2019-04-12 14:38:50
Version 1 published

Accepted as a Level 1 sequence at IARC Meeting 34 on March 29, 2019.

Mats Ohlin
2019-05-16 21:48:45
Version 2 published

IMGT allele name added

William Lees
2023-07-10 11:24:35
Version 3 published

Bulk upload of sequences for the AIRR-C Human IG germline sets

Changes from previous version

CuratorWilliam Lees
Curator addressDept. of Immunotechnology, Lund University, Medicon Village building 406, S-22381 Lund, SwedenBirkbeck College, University of London, Malet Street, London
Sequence NameIGHV1-58*i01IGHV1-58*03
Alternative namesIGHV1-58*p04IGHV1-58*i01
Species subgroup
Subgroup type
Allele Designationi0103
Full Sequence
Gene start1
Gene end295
CDR1 Start76
CDR1 End99
CDR2 Start151
CDR2 End174
CDR3 Start289
Paralog RepFalse
3' ExtensionA
5' Extension


All published versions of this sequence.

Sequence NameIMGT NameVersionDate