Species | Homo sapiens |
Species subgroup | |
Subgroup type | |
Sequence Name | IGHV1-58*i01 |
IUIS Name | |
Alternative names | IGHV1-58*p04 |
Affirmation Level | 1 |
Full Sequence | |
Coding Sequence | |
Functionality | F |
Inference Type | Rearranged Only |
Mapped | |
Paralogs | |
Paralog Rep |
Un-rearranged sequence observations that support this sequence:
Click here to review supporting data in VDJbase.
Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.
CDR1 Start | |
CDR1 End | |
CDR2 Start | |
CDR2 End | |
CDR3 Start |
Sequence ID | A00014 |
Curator | |
Curator address | Dept. of Immunotechnology, Lund University, Medicon Village building 406, S-22381 Lund, Sweden |
Version | 1 |
Release Date | 2019-04-12 |
Release Notes | Accepted as a Level 1 sequence at IARC Meeting 34 on March 29, 2019. |
Locus | IGH |
Sequence Type | V |
Gene Subgroup | 1 |
Gene Designation | 58 |
Allele Designation | i01 |
Gene start | |
Gene end |
Notes are added by IARC reviewers.
This sequence represents IGHV1-58*01+G33A in the IMGT numbering system. The committee noted a rearrangement frequency of 0.15%, with 178 alignments including 127 perfect matches to the inferred allele. There was abundant variation in the CDR3 regions of the aligned sequences. The genotype showed the individual to be heterozygous at the IGHV1-58 locus, with the alternative IGHV1-58*01 allele being associated with 214 sequences for an allele ratio of 45:55. This sequence has previously been catalogued by IgPdb as IGHV1-58*p04, though the IgPdb sequence is derived from the S0008 dataset. All members of the committee agreed that the sequence should be accepted as a Level 1 sequence at IARC Meeting 34 on March 29, 2019. In line with previous policy, the submitted sequence will be recognized up to and including nucleotide 319. A trailing “.” indicates IARC’s opinion that the sequences likely to contain an additional/additional 3’ nucleotide(s) for which there is insufficient evidence to make an affirmation. |
History logs the times and reasons for the publication of each version of this sequence.
Mats Ohlin 2019-04-12 14:38:50 | Version 1 published Accepted as a Level 1 sequence at IARC Meeting 34 on March 29, 2019. |
All published versions of this sequence.
Sequence Name | IMGT Name | Version | Date |
---|---|---|---|
IGHV1-58*i01 | 1 | 2019-04-12 | |
IGHV1-58*i01 | IGHV1-58*03 | 2 | 2019-05-16 |
IGHV1-58*03 | IGHV1-58*03 | 3 | 2023-07-10 |