This allele was affirmed at IARC meeting 99 on May 9th, 2022. TRBV19*01_A24G has been inferred in six genotypes in the VDJbase P4 data set, including in VDJbase P4_I24_S1, a haplotypable data set (based on heterozygocity in TRBJ1-6). The genotype is also implied to carry TRBV19*01. No other gene in the IMGT database is closely related to these alleles of TRBV19. The novel allele is the most expressed allele in the repertoire (53% allelic frequency; 0.71% of the total error-free population). It is represented by 240 error-free sequences and 202 unique CDR3s in the error-free set. Haplotyping based on allelic diversity in TRBJ1-6 demonstrates perfect separation from TRBV19*01. IARC affirms the sequence at Level 1 up to and including base 322. It is acknowledged that the allele most likely carries 4 additional bases, typically TAGA, at base positions 323-326. Trailing “.” indicates IARC’s opinion that the sequence is likely to contain additional 3’-nucleotides for which there is insufficient evidence to make an affirmation.