Species subgroup
Subgroup typenone
Sequence NameTRBV19*i01
Alternative namesTRBV19*01 A24G
Affirmation Level1
Full Sequence
Coding Sequence
Inference TypeRearranged
Paralog Rep


The table below lists submissions to IARC , and the inferences within them, on which this IARC-affirmed sequence is based.

'Sequence Match' indicates whether the inference exactly matches the sequence, and clicking on the tick or cross will provide an alignment. Mismatches may be caused, for example, by the inclusion of leader sequences, or nucleotides in the inference which do not in IARC's opinion have sufficient evidence for inclusion in the sequence.

Submission IDAccession NoSubject IDGenotype NameSequence NameSequence Match
S00036 OW166726S24P4_I24_S1_ogrdb_reportTRBV19*01_A24G

Observations in VDJbase

Inferred sequences in VDJbase that match this sequence:

VDJbase Allele NameSubjectsSequence Match
TRBV19*01_a24g 0

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

No Items

Non-Core Regions

UTR 5' Start
UTR 5' End
L-PART1 Start
L-PART2 Start


3' Extension
3' start
3' end
5' start
5' end

Additional Information

Sequence IDA02563
CuratorMats Ohlin
Curator addressDept. of Immunotechnology, Lund University, Medicon Village building 406, S-22381 Lund, Sweden
Release Date2022-07-26
Release Notes

The allele was published by IARC on July 26th, 2022.

Sequence TypeV
Gene Subgroup19
Gene Designation19
Allele Designationi01


Individuals acknowledged as contributing to this sequence:

NameInstitutionORCID ID
William LeesBirkbeck College, University of London, Malet Street, London
Ayelet PeresBar-Ilan University, Ramat-Gan, Israel
Gur YaariBar-Ilan University, Ramat-Gan, Israel


Notes are added by IARC reviewers.

This allele was affirmed at IARC meeting 99 on May 9th, 2022. TRBV19*01_A24G has been inferred in six genotypes in the VDJbase P4 data set, including in VDJbase P4_I24_S1, a haplotypable data set (based on heterozygocity in TRBJ1-6). The genotype is also implied to carry TRBV19*01. No other gene in the IMGT database is closely related to these alleles of TRBV19. The novel allele is the most expressed allele in the repertoire (53% allelic frequency; 0.71% of the total error-free population). It is represented by 240 error-free sequences and 202 unique CDR3s in the error-free set. Haplotyping based on allelic diversity in TRBJ1-6 demonstrates perfect separation from TRBV19*01. IARC affirms the sequence at Level 1 up to and including base 322. It is acknowledged that the allele most likely carries 4 additional bases, typically TAGA, at base positions 323-326. Trailing “.” indicates IARC’s opinion that the sequence is likely to contain additional 3’-nucleotides for which there is insufficient evidence to make an affirmation.


No Items


History logs the times and reasons for the publication of each version of this sequence.

Mats Ohlin
2022-07-26 09:52:44
Version 1 published

The allele was published by IARC on July 26th, 2022.


All published versions of this sequence.

Sequence NameIMGT NameAlternative namesInference TypeAffirmation LevelSpecies subgroupSubgroup typeVersionDate
TRBV19*i01TRBV19*01 A24GRearranged1none12022-07-26