Details

SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGLV10-54*i01
IUIS NameIGLV10-54*04
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityF
Inference TypeRearranged Only
Mapped
Paralogs
Paralog Rep

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

No Items

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start76
CDR1 End99
CDR2 Start151
CDR2 End159
CDR3 Start268

Additional Information

Sequence IDA00055
Curator
Curator addressSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney Australia
Version1
Release Date2020-07-30
Release Notes

Submission published by IARC on July 30th 2020.

LocusIGL
Sequence TypeV
Gene Subgroup10
Gene Designation54
Allele Designationi01
Gene start1
Gene end294

Acknowledgements

Individuals acknowledged as contributing to this sequence:

NameInstitutionORCID ID
Néstor Vázquez BernatKarolinska Institutet SE-171 77 Stockholm

Notes

Notes are added by IARC reviewers.

The sequence was first affirmed at IARC Meeting 53 on April 14th 2020, where it was noted:

“The sequence was seen in 1.79% of all unmutated rearrangements, with 11279 sequences including 2138 perfect matches to the inferred allele. There was abundant variation in the CDR3 regions of the aligned sequences. The IGLV10-54*01 allele was also present in the genotype, at a similar frequency (1.77% of all unmutated sequences; 7826 sequences; 2117 unmutated sequences). Haplotype data is unavailable. Plots of the final 3’ nucleotides showed a high level of variability, making it impossible to determine the final three nucleotides with certainty. The sequence, up to and including nucleotide 339, was affirmed as a Level 1 sequence. Uncertainty regarding nucleotides 340-341 will be indicated in IARC and OGRDB publications by two dots at the end of the affirmed sequence.”

Attachments

Supplementary Files
 

History

History logs the times and reasons for the publication of each version of this sequence.

Andrew Collins
2020-07-30 12:58:46
Version 1 published

Submission published by IARC on July 30th 2020.

Mats Ohlin
2021-04-29 22:33:15
IMGT Name updated to IGLV10-54*04

IMGT Name updated.

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGLV10-54*i01IGLV10-54*0412020-07-30
IGLV10-54*04IGLV10-54*0422023-07-10
IGLV10-54*04IGLV10-54*0432024-02-22