This inference was considered at IARC Meeting 49 on February 4th 2020, at which it was noted:

The sequence was seen in 0.3% of all unmutated rearrangements, with 747 sequences including 538 perfect matches to the inferred allele. There was abundant variation in the CDR3 regions of the aligned sequences, though relatively large numbers of sequences were clonally related (42 “Unique CDR3s with unmutated”). The IGKV1D-8*01 allele was also present in the genotype, at a similar frequency (0.4% of all unmutated sequences; 976 sequences; 758 unmutated sequences). It was noted that the select set available in SRA/ENA is very limited in size (essentially only representing 2 different rearrangements, either involving IGKJ1 or IGKJ2) as only full-length sequences (covering all bases of the V gene up to and including base 335) had been included in the submitted set. IGKV1-8*01 was also present at high frequency (7743 sequences), but this sequence has 12 nucleotide differences to the inference under consideration. Haplotype data is unavailable. Plots of the final 3’ nucleotides showed a high level of variability, making it impossible to determine the final three nucleotides with certainty. The sequence, up to and including nucleotide 332, was affirmed as a Level 1 sequence. Uncertainty regarding nucleotides 333-335 will be indicated in IARC and OGRDB publications by three dots at the end of the affirmed sequence.