| Species | Homo sapiens |
| Species subgroup | |
| Subgroup type | |
| Sequence Name | IGHV3-49*05 |
| IUIS Name | IGHV3-49*05 |
| Alternative names | |
| Affirmation Level | 1 |
| Full Sequence | |
| Coding Sequence | |
| Functionality | ORF |
| Inference Type | Unrearranged |
| Mapped | True |
| Paralogs | |
| Paralog Rep | False |
Un-rearranged sequence observations that support this sequence:
| Accession | Type | Repository | Start | End | Coding Sequence | SC Coding Sequence |
|---|---|---|---|---|---|---|
| HM855748 | Nonlocational | GenBank | 11 | 351 | ||
| SRX19354839 | V | Genbank | 1 | 501 |
Click here to review supporting data in VDJbase.
Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.
| CDR1 Start | 236 |
| CDR1 End | 259 |
| CDR2 Start | 311 |
| CDR2 End | 340 |
| CDR3 Start | 455 |
| UTR 5' Start | |
| UTR 5' End | |
| L-PART1 Start | 1 |
| L-PART1 End | 46 |
| L_PART1 | ATGGAGTTTGGGCTTAGCTGGGTTTTCCTTGTTGCTATTTTAAAAG |
| L-PART2 Start | 150 |
| L-PART2 End | 160 |
| L_PART2 | GTGTCCAATGT |
| v_rs_start | 463 |
| v_rs_end | 501 |
| V_HEPTAMER | CACAGTG |
| V_NONAMER | ACACAAACC |
| Exon 1 Start | |
| Exon 1 End | |
| Exon 2 Start | |
| Exon 2 End | |
| Exon 3 Start | |
| Exon 3 End | |
| Exon 4 Start | |
| Exon 4 End | |
| Exon 5 Start | |
| Exon 5 End | |
| Exon 6 Start | |
| Exon 6 End | |
| Exon 7 Start | |
| Exon 7 End | |
| Exon 8 Start | |
| Exon 8 End | |
| Exon 9 Start | |
| Exon 9 End | |
| UTR 3' Start | |
| UTR 3' End |
| 3' Extension | |
| 3' start | |
| 3' end | |
| 5' start | |
| 5' end |
| Sequence ID | A02732 |
| Curator | William Lees |
| Curator address | Clareo Biosciences, Louisville, Kentucky, USA |
| Version | 3 |
| Release Date | 2026-05-27 |
| Release Notes | Repeat – had to roll back yesterday’s changes. Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names |
| Locus | IGH |
| Sequence Type | V |
| Gene Subgroup | 3 |
| Gene Designation | 49 |
| Allele Designation | 05 |
| Gene start | 161 |
| Gene end | 462 |
Notes are added by IARC reviewers.
| Sequence annotation is based on Genbank sample HM855748 Additional information for this sequence was imported into OGRDB via bulk update with the following notes: |
History logs the times and reasons for the publication of each version of this sequence.
| William Lees 2023-07-10 11:24:39 | Version 1 published Bulk upload of sequences for the AIRR-C Human IG germline sets |
| William Lees 2024-02-24 08:32:06 | Version 2 published Note alternatve L-PART2 sequence observed in other contexts |
| William Lees 2026-05-27 07:52:10 | Version 3 published Repeat – had to roll back yesterday’s changes. Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names |
| v2 | v3 | |
|---|---|---|
| Curator address | Birkbeck College, University of London, Malet Street, London | Clareo Biosciences, Louisville, Kentucky, USA |
| Inference Type | Unrearranged and Rearranged | Unrearranged |
| Subgroup type | none | |
| Full Sequence | ||
| Gene start | 22 | 161 |
| Gene end | 323 | 462 |
| L-PART1 Start | 1 | |
| L-PART1 End | 46 | |
| L-PART2 Start | 11 | 150 |
| L-PART2 End | 21 | 160 |
| CDR1 Start | 97 | 236 |
| CDR1 End | 120 | 259 |
| CDR2 Start | 172 | 311 |
| CDR2 End | 201 | 340 |
| CDR3 Start | 316 | 455 |
| v_rs_start | 324 | 463 |
| v_rs_end | 352 | 501 |
| 3' Extension | ||
| 5' Extension | ||
| curational_tags | likely_full-length | likely_full_length |
| Notes | changed |
All published versions of this sequence.
| Sequence Name | IMGT Name | Version | Date |
|---|---|---|---|
| IGHV3-49*05 | IGHV3-49*05 | 1 | 2023-07-10 |
| IGHV3-49*05 | IGHV3-49*05 | 2 | 2024-02-24 |
| IGHV3-49*05 | IGHV3-49*05 | 3 | 2026-05-27 |