Details

SpeciesHuman
Species subgroup
Subgroup typenone
Sequence NameIGHV3-49*05
IUIS NameIGHV3-49*05
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityORF
Inference TypeGenomic and rearranged
MappedTrue
Paralogs
Paralog RepFalse

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

AccessionTypeRepositoryStartEnd
HM855748NonlocationalGenBank11351

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start97
CDR1 End120
CDR2 Start172
CDR2 End201
CDR3 Start316

Non-Core Regions

UTR 5' Start
UTR 5' End
L-PART1 Start
L-PART1 End
L_PART1
L-PART2 Start11
L-PART2 End21
L_PART2GTGTCCAGTGT
v_rs_start324
v_rs_end352
V_HEPTAMER
V_NONAMER

Extension

3' Extension
3' start
3' end
5' start
5' end

Additional Information

Sequence IDA02732
CuratorWilliam Lees
Curator addressBirkbeck College, University of London, Malet Street, London
Version2
Release Date2024-02-24
Release Notes

Note alternatve L-PART2 sequence observed in other contexts

LocusIGH
Sequence TypeV
Gene Subgroup3
Gene Designation49
Allele Designation05

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Sequence annotation is based on Genbank sample HM855748
VDJbase example haplotype: P1_I100
Mapped by P1_I100 haplotype
An alternative L-PART2 sequence GTGTCCAATGT is observed in Rodriguez et al., who report both forms. This alternative is observed by Huang, Thörnqvist and Ohlin, 2021

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

William Lees
2023-07-10 11:24:39
Version 1 published

Bulk upload of sequences for the AIRR-C Human IG germline sets

William Lees
2024-02-24 08:32:06
Version 2 published

Note alternatve L-PART2 sequence observed in other contexts

Changes from previous version

v1v2
Subgroup typenone
Codon Frame1
3' Extension
5' Extension
Noteschanged

Versions

All published versions of this sequence.

Sequence NameIMGT NameAlternative namesInference TypeAffirmation LevelSpecies subgroupSubgroup typeGene startGene endUTR 5' StartUTR 5' EndL-PART1 StartL-PART1 EndL-PART2 StartL-PART2 EndCDR1 StartCDR1 EndCDR2 StartCDR2 EndCDR3 Startv_rs_startv_rs_endd_rs_3_prime_startd_rs_3_prime_endd_rs_5_prime_startd_rs_5_prime_endj_rs_startj_rs_endCodon FrameVersionDate
IGHV3-49*05IGHV3-49*05Genomic and rearranged12232311219712017220131632435212023-07-10
IGHV3-49*05IGHV3-49*05Genomic and rearranged1none22323112197120172201316324352122024-02-24