Details


Species	Human
Species subgroup
Subgroup type	none
Sequence Name	IGHV1-2*05
IUIS Name	IGHV1-2*05
Alternative names
Affirmation Level	1
Full Sequence
Coding Sequence
Functionality	ORF
Inference Type	Genomic Only
Mapped	False
Paralogs
Paralog Rep	False

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

Accession	Type	Repository	Start	End
HM855681	Nonlocational	GenBank	320	24

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation


CDR1 Start	105
CDR1 End	128
CDR2 Start	180
CDR2 End	203
CDR3 Start	318

Non-Core Regions


UTR 5' Start
UTR 5' End
L-PART1 Start
L-PART1 End
L_PART1
L-PART2 Start
L-PART2 End
L_PART2
v_rs_start	326
v_rs_end	354
V_HEPTAMER
V_NONAMER

Extension


3' Extension
3' start
3' end
5' start
5' end

Additional Information


Sequence ID	A02959
Curator	William Lees
Curator address	Birkbeck College, University of London, Malet Street, London
Version	2
Release Date	2024-02-23
Release Notes	Remove the questionable annotation of L-PART1
Locus	IGH
Sequence Type	V
Gene Subgroup	1
Gene Designation	2
Allele Designation	05

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.


Information for this sequence was imported into OGRDB via bulk update with the following notes: Sequence annotation is based on Genbank sample HM855681. Sequence observed in data from Rodriguez et al. 2023 as reported in VDJbase (26 samples). Example subject: P25_I25. Annotation of L-PART2 removed as this is in conflict with that observed by Huang, Thörnqvist and Ohlin, 2021

Information for this sequence was imported into OGRDB via bulk update with the following notes:
Sequence annotation is based on Genbank sample HM855681. Sequence observed in data from Rodriguez et al.
2023 as reported in VDJbase (26 samples). Example subject: P25_I25.

Annotation of L-PART2 removed as this is in conflict with that observed by Huang, Thörnqvist and Ohlin, 2021

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.


William Lees 2023-08-15 12:54:48	Version 1 published Sequences added following discussion at IARC meeting on 9th August 2023


William Lees 2024-02-23 15:40:50	Version 2 published Remove the questionable annotation of L-PART1

Changes from previous version

	v1	v2
Subgroup type		none
L-PART2 Start	20
L-PART2 End	29
Codon Frame		1
3' Extension
5' Extension
Notes		changed

Versions

All published versions of this sequence.

Sequence Name	IMGT Name	Alternative names	Inference Type	Affirmation Level	Species subgroup	Subgroup type	Gene start	Gene end	UTR 5' Start	UTR 5' End	L-PART1 Start	L-PART1 End	L-PART2 Start	L-PART2 End	CDR1 Start	CDR1 End	CDR2 Start	CDR2 End	CDR3 Start	v_rs_start	v_rs_end	d_rs_3_prime_start	d_rs_3_prime_end	d_rs_5_prime_start	d_rs_5_prime_end	j_rs_start	j_rs_end	Codon Frame	Version	Date
IGHV1-2*05	IGHV1-2*05		Genomic Only	1			30	325					20	29	105	128	180	203	318	326	354								1	2023-08-15
IGHV1-2*05	IGHV1-2*05		Genomic Only	1		none	30	325							105	128	180	203	318	326	354							1	2	2024-02-23