Details

SpeciesHomo sapiens
Species subgroup
Subgroup typenone
Sequence NameIGKV2D-40*01
IUIS NameIGKV2D-40*01
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityORF
Inference TypeGenomic Only
MappedTrue
ParalogsIGKV2-40*01
Paralog RepTrue

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

AccessionTypeRepositoryStartEndCoding SequenceSC Coding Sequence
X93631NonlocationalGenBank1305
AC244255NonlocationalGenBank198406198954
NG_000833NonlocationalGenBank396335397098
GRCh38:NC_000002.12LocationalGenBank994398995161

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start510
CDR1 End545
CDR2 Start597
CDR2 End605
CDR3 Start714

Non-Core Regions

UTR 5' Start
UTR 5' End
L-PART1 Start1
L-PART1 End49
L_PART1ATGAGGCTCCCTGCTCAGCTCCTGGGGCTGCTAATGCTCTGGGTCCCTG
L-PART2 Start421
L-PART2 End431
L_PART2GATCCAGTGAG
v_rs_start737
v_rs_end764
V_HEPTAMERCACAGTG
V_NONAMERACAGAAACC
Exon 1 Start
Exon 1 End
Exon 2 Start
Exon 2 End
Exon 3 Start
Exon 3 End
Exon 4 Start
Exon 4 End
Exon 5 Start
Exon 5 End
Exon 6 Start
Exon 6 End
Exon 7 Start
Exon 7 End
Exon 8 Start
Exon 8 End
Exon 9 Start
Exon 9 End
UTR 3' Start
UTR 3' End

Extension

3' Extension
3' start
3' end
5' start
5' end

Additional Information

Sequence IDA02843
CuratorWilliam Lees
Curator addressBirkbeck College, University of London, Malet Street, London
Version2
Release Date2026-05-27
Release Notes

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P27 (PMID38844673), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

LocusIGK
Sequence TypeV
Gene Subgroup2D
Gene Designation40
Allele Designation01
Gene start432
Gene end736

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Information for this sequence was imported into OGRDB via bulk update with the following notes:
Sequence annotation is based on Genbank sample NG_000833

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

William Lees
2023-07-10 11:24:44
Version 1 published

Bulk upload of sequences for the AIRR-C Human IG germline sets

William Lees
2026-05-27 08:07:26
Version 2 published

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P27 (PMID38844673), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

Changes from previous version

v1v2
Inference TypeUnrearranged OnlyGenomic Only
Subgroup typenone
SC Coding SequenceNoneNone
Codon Frame1
Paralog RepFalseTrue
3' Extension
5' Extension

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGKV2D-40*01IGKV2D-40*0112023-07-10
IGKV2D-40*01IGKV2D-40*0122026-05-27