Details

SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGHV3-53*04
IUIS NameIGHV3-53*04
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityORF
Inference TypeUnrearranged
MappedTrue
Paralogs
Paralog RepFalse

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

AccessionTypeRepositoryStartEndCoding SequenceSC Coding Sequence
HM855879NonlocationalGenBank1325
SRX19354803VGenbank1490

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start234
CDR1 End257
CDR2 Start309
CDR2 End329
CDR3 Start444

Non-Core Regions

UTR 5' Start
UTR 5' End
L-PART1 Start1
L-PART1 End46
L_PART1ATGGAGTTTTGGCTGAGCTGGGTTTTCCTTGTTGCTATTTTAAAAG
L-PART2 Start148
L-PART2 End158
L_PART2GTGTCCAGTGT
v_rs_start452
v_rs_end490
V_HEPTAMERCACAGTG
V_NONAMERACACAAACC
Exon 1 Start
Exon 1 End
Exon 2 Start
Exon 2 End
Exon 3 Start
Exon 3 End
Exon 4 Start
Exon 4 End
Exon 5 Start
Exon 5 End
Exon 6 Start
Exon 6 End
Exon 7 Start
Exon 7 End
Exon 8 Start
Exon 8 End
Exon 9 Start
Exon 9 End
UTR 3' Start
UTR 3' End

Extension

3' Extension
3' start
3' end
5' start
5' end

Additional Information

Sequence IDA02735
CuratorWilliam Lees
Curator addressClareo Biosciences, Louisville, Kentucky, USA
Version2
Release Date2026-05-27
Release Notes

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

LocusIGH
Sequence TypeV
Gene Subgroup3
Gene Designation53
Allele Designation04
Gene start159
Gene end451

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Information for this sequence was imported into OGRDB via bulk update with the following notes:
Sequence annotation is based on Genbank sample HM855879
VDJbase example haplotype: P1_I12
Mapped by P1_I12 haplotype

Additional information for this sequence was imported into OGRDB via bulk update with the following notes:
Annotation is based on VDJbase record P25_I57_S1 for sample SC-21 (Genbank: SRX19354803).

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

William Lees
2023-07-10 11:24:39
Version 1 published

Bulk upload of sequences for the AIRR-C Human IG germline sets

William Lees
2026-05-27 07:52:06
Version 2 published

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

Changes from previous version

v1v2
Curator addressBirkbeck College, University of London, Malet Street, LondonClareo Biosciences, Louisville, Kentucky, USA
Inference TypeUnrearranged and RearrangedUnrearranged
Full Sequence
Gene start29159
Gene end321451
L-PART1 Start1
L-PART1 End46
L-PART2 Start18148
L-PART2 End28158
CDR1 Start104234
CDR1 End127257
CDR2 Start179309
CDR2 End199329
CDR3 Start314444
v_rs_start322452
v_rs_end350490
curational_tagslikely_full-lengthlikely_full_length
Noteschanged

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGHV3-53*04IGHV3-53*0412023-07-10
IGHV3-53*04IGHV3-53*0422026-05-27