Details

SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGHV1-69*01
IUIS NameIGHV1-69*01
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityORF
Inference TypeUnrearranged
MappedTrue
ParalogsIGHV1-69D*01
Paralog RepTrue

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

AccessionTypeRepositoryStartEndCoding SequenceSC Coding Sequence
ON052038NonlocationalGenBank43510
SRX19354816VGenbank1478

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start219
CDR1 End242
CDR2 Start294
CDR2 End317
CDR3 Start432

Non-Core Regions

UTR 5' Start
UTR 5' End
L-PART1 Start1
L-PART1 End46
L_PART1ATGGACTGGACCTGGAGGTTCCTCTTTGTGGTGGCAGCAGCTACAG
L-PART2 Start133
L-PART2 End143
L_PART2GTGTCCAGTCC
v_rs_start440
v_rs_end478
V_HEPTAMERCACAGTG
V_NONAMERTCAGAAACC
Exon 1 Start
Exon 1 End
Exon 2 Start
Exon 2 End
Exon 3 Start
Exon 3 End
Exon 4 Start
Exon 4 End
Exon 5 Start
Exon 5 End
Exon 6 Start
Exon 6 End
Exon 7 Start
Exon 7 End
Exon 8 Start
Exon 8 End
Exon 9 Start
Exon 9 End
UTR 3' Start
UTR 3' End

Extension

3' Extension
3' start
3' end
5' start
5' end

Additional Information

Sequence IDA02664
CuratorWilliam Lees
Curator addressClareo Biosciences, Louisville, Kentucky, USA
Version2
Release Date2026-05-27
Release Notes

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

LocusIGH
Sequence TypeV
Gene Subgroup1
Gene Designation69
Allele Designation01
Gene start144
Gene end439

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Information for this sequence was imported into OGRDB via bulk update with the following notes:
Sequence annotation is based on Genbank sample ON052038
VDJbase example haplotype: P1_I22_S1
Mapped by P1_I22 haplotype

Additional information for this sequence was imported into OGRDB via bulk update with the following notes:
Annotation is based on VDJbase record P25_I122_S1 for sample W-55 (Genbank: SRX19354816).

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

William Lees
2023-07-10 11:24:35
Version 1 published

Bulk upload of sequences for the AIRR-C Human IG germline sets

William Lees
2026-05-27 07:52:09
Version 2 published

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

Changes from previous version

v1v2
Curator addressBirkbeck College, University of London, Malet Street, LondonClareo Biosciences, Louisville, Kentucky, USA
Inference TypeUnrearranged and RearrangedUnrearranged
Full Sequence
Gene start186144
Gene end481439
L-PART1 Start1
L-PART1 End46
L-PART2 Start175133
L-PART2 End185143
CDR1 Start261219
CDR1 End284242
CDR2 Start336294
CDR2 End359317
CDR3 Start474432
v_rs_start482440
v_rs_end512478
curational_tagslikely_full-lengthlikely_full_length
Noteschanged

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGHV1-69*01IGHV1-69*0112023-07-10
IGHV1-69*01IGHV1-69*0122026-05-27