Details

SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGHV7-4-1*02
IUIS NameIGHV7-4-1*02
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityORF
Inference TypeUnrearranged
MappedTrue
Paralogs
Paralog RepFalse

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

AccessionTypeRepositoryStartEndCoding SequenceSC Coding Sequence
MG719329NonlocationalGenBank49438
HM855930NonlocationalGenBank1330
SRX19354902VGenbank1476

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start217
CDR1 End240
CDR2 Start292
CDR2 End315
CDR3 Start430

Non-Core Regions

UTR 5' Start
UTR 5' End
L-PART1 Start1
L-PART1 End46
L_PART1ATGGACTGGACCTGGAGGATCCTCTTCTTGGTGGCAGCAGCAACAG
L-PART2 Start131
L-PART2 End141
L_PART2GTGCCCACTCC
v_rs_start438
v_rs_end476
V_HEPTAMERCACAGTG
V_NONAMERTCAAAAACC
Exon 1 Start
Exon 1 End
Exon 2 Start
Exon 2 End
Exon 3 Start
Exon 3 End
Exon 4 Start
Exon 4 End
Exon 5 Start
Exon 5 End
Exon 6 Start
Exon 6 End
Exon 7 Start
Exon 7 End
Exon 8 Start
Exon 8 End
Exon 9 Start
Exon 9 End
UTR 3' Start
UTR 3' End

Extension

3' Extension
3' start
3' end
5' start
5' end

Additional Information

Sequence IDA02783
CuratorWilliam Lees
Curator addressClareo Biosciences, Louisville, Kentucky, USA
Version2
Release Date2026-05-27
Release Notes

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

LocusIGH
Sequence TypeV
Gene Subgroup7-4
Gene Designation1
Allele Designation02
Gene start142
Gene end437

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Information for this sequence was imported into OGRDB via bulk update with the following notes:
Sequence annotation is based on Genbank sample MG719329
VDJbase example haplotype: P1_I70

Additional information for this sequence was imported into OGRDB via bulk update with the following notes:
Annotation is based on VDJbase record P25_I107_S1 for sample W-34 (Genbank: SRX19354902).

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

William Lees
2023-07-10 11:24:42
Version 1 published

Bulk upload of sequences for the AIRR-C Human IG germline sets

William Lees
2026-05-27 07:52:09
Version 2 published

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

Changes from previous version

v1v2
Curator addressBirkbeck College, University of London, Malet Street, LondonClareo Biosciences, Louisville, Kentucky, USA
MappedFalseTrue
Inference TypeUnrearranged and RearrangedUnrearranged
Full Sequence
Gene start125142
Gene end420437
L-PART1 Start1
L-PART1 End46
L-PART2 Start114131
L-PART2 End124141
CDR1 Start200217
CDR1 End223240
CDR2 Start275292
CDR2 End298315
CDR3 Start413430
v_rs_start421438
v_rs_end449476
curational_tagslikely_full-lengthlikely_full_length
Noteschanged

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGHV7-4-1*02IGHV7-4-1*0212023-07-10
IGHV7-4-1*02IGHV7-4-1*0222026-05-27