Details

SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGHV1-18*01
IUIS NameIGHV1-18*01
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityORF
Inference TypeUnrearranged
MappedTrue
Paralogs
Paralog RepFalse

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

AccessionTypeRepositoryStartEndCoding SequenceSC Coding Sequence
M99641NonlocationalGenBank47522
HM855840NonlocationalGenBank1329
ON052029NonlocationalGenBank208670
SRX19354839VGenbank1476

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start217
CDR1 End240
CDR2 Start292
CDR2 End315
CDR3 Start430

Non-Core Regions

UTR 5' Start
UTR 5' End
L-PART1 Start1
L-PART1 End46
L_PART1ATGGACTGGACCTGGAGCATCCTTTTCTTGGTGGCAGCAGCAACAG
L-PART2 Start131
L-PART2 End141
L_PART2GTGCCCACTCC
v_rs_start438
v_rs_end476
V_HEPTAMERCACAGTG
V_NONAMERTCAGAAACC
Exon 1 Start
Exon 1 End
Exon 2 Start
Exon 2 End
Exon 3 Start
Exon 3 End
Exon 4 Start
Exon 4 End
Exon 5 Start
Exon 5 End
Exon 6 Start
Exon 6 End
Exon 7 Start
Exon 7 End
Exon 8 Start
Exon 8 End
Exon 9 Start
Exon 9 End
UTR 3' Start
UTR 3' End

Extension

3' Extension
3' start
3' end
5' start
5' end

Additional Information

Sequence IDA02646
CuratorWilliam Lees
Curator addressClareo Biosciences, Louisville, Kentucky, USA
Version2
Release Date2026-05-27
Release Notes

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

LocusIGH
Sequence TypeV
Gene Subgroup1
Gene Designation18
Allele Designation01
Gene start142
Gene end437

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Information for this sequence was imported into OGRDB via bulk update with the following notes:
Sequence annotation is based on Genbank sample M99641
VDJbase example haplotype: P1_I10_S1

Additional information for this sequence was imported into OGRDB via bulk update with the following notes:
Annotation is based on VDJbase record P25_I143_S1 for sample W-86 (Genbank: SRX19354839).

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

William Lees
2023-07-10 11:24:35
Version 1 published

Bulk upload of sequences for the AIRR-C Human IG germline sets

William Lees
2026-05-27 07:52:08
Version 2 published

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

Changes from previous version

v1v2
Curator addressBirkbeck College, University of London, Malet Street, LondonClareo Biosciences, Louisville, Kentucky, USA
Inference TypeUnrearranged and RearrangedUnrearranged
Full Sequence
Gene start188142
Gene end483437
L-PART1 Start1
L-PART1 End46
L-PART2 Start177131
L-PART2 End187141
CDR1 Start263217
CDR1 End286240
CDR2 Start338292
CDR2 End361315
CDR3 Start476430
v_rs_start484438
v_rs_end522476
curational_tagslikely_full-lengthlikely_full_length
Noteschanged

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGHV1-18*01IGHV1-18*0112023-07-10
IGHV1-18*01IGHV1-18*0122026-05-27