Details

SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGHV1-45*03
IUIS NameIGHV1-45*03
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityORF
Inference TypeUnrearranged
MappedTrue
Paralogs
Paralog RepFalse

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

AccessionTypeRepositoryStartEndCoding SequenceSC Coding Sequence
MG719320NonlocationalGenBank54439
SRX19354849VGenbank1477

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start218
CDR1 End241
CDR2 Start293
CDR2 End316
CDR3 Start431

Non-Core Regions

UTR 5' Start
UTR 5' End
L-PART1 Start1
L-PART1 End46
L_PART1ATGGACTGGACCTGGAGAATCCTCTTCTTGGTGGCAGCAGCCACAG
L-PART2 Start132
L-PART2 End142
L_PART2ATGCCTACTCC
v_rs_start439
v_rs_end477
V_HEPTAMERCACAGTG
V_NONAMERTCAGAAACC
Exon 1 Start
Exon 1 End
Exon 2 Start
Exon 2 End
Exon 3 Start
Exon 3 End
Exon 4 Start
Exon 4 End
Exon 5 Start
Exon 5 End
Exon 6 Start
Exon 6 End
Exon 7 Start
Exon 7 End
Exon 8 Start
Exon 8 End
Exon 9 Start
Exon 9 End
UTR 3' Start
UTR 3' End

Extension

3' Extension
3' start
3' end
5' start
5' end

Additional Information

Sequence IDA02657
CuratorWilliam Lees
Curator addressClareo Biosciences, Louisville, Kentucky, USA
Version2
Release Date2026-05-27
Release Notes

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

LocusIGH
Sequence TypeV
Gene Subgroup1
Gene Designation45
Allele Designation03
Gene start143
Gene end438

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Information for this sequence was imported into OGRDB via bulk update with the following notes:
Sequence annotation is based on Genbank sample MG719320
VDJbase example haplotype: P1_I41 (2 exact matches)

Additional information for this sequence was imported into OGRDB via bulk update with the following notes:
Annotation is based on VDJbase record P25_I59_S1 for sample SC-24 (Genbank: SRX19354849).

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

William Lees
2023-07-10 11:24:35
Version 1 published

Bulk upload of sequences for the AIRR-C Human IG germline sets

William Lees
2026-05-27 07:52:08
Version 2 published

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

Changes from previous version

v1v2
Curator addressBirkbeck College, University of London, Malet Street, LondonClareo Biosciences, Louisville, Kentucky, USA
MappedFalseTrue
Inference TypeUnrearranged and RearrangedUnrearranged
Full Sequence
Gene start126143
Gene end421438
L-PART1 Start1
L-PART1 End46
L-PART2 Start115132
L-PART2 End125142
CDR1 Start201218
CDR1 End224241
CDR2 Start276293
CDR2 End299316
CDR3 Start414431
v_rs_start422439
v_rs_end450477
curational_tagslikely_full-lengthlikely_full_length
Noteschanged

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGHV1-45*03IGHV1-45*0312023-07-10
IGHV1-45*03IGHV1-45*0322026-05-27