Sequence IGHV2-70D*04
Details
| Species | Homo sapiens |
| Species subgroup | |
| Subgroup type | none |
| Sequence Name | IGHV2-70D*04 |
| IUIS Name | IGHV2-70D*04 |
| Alternative names | |
| Affirmation Level | 1 |
| Full Sequence | |
| Coding Sequence | |
| Functionality | ORF |
| Inference Type | Genomic Only |
| Mapped | True |
| Paralogs | IGHV2-70*04 |
| Paralog Rep | True |
Un-rearranged Observations
Un-rearranged sequence observations that support this sequence:
| Accession | Type | Repository | Start | End | Coding Sequence | SC Coding Sequence |
|---|---|---|---|---|---|---|
| MG719337 | Nonlocational | GenBank | 58 | 540 | ||
| ON052045 | Nonlocational | GenBank | 292 | 727 | ||
| GRCh38:CM000676.2 | Locational | GenBank | 155828 | 156310 | ||
| SRX19354905 | V | Genbank | 1 | 483 |
Observations in AIRR-seq Repertoires
Click here to review supporting data in VDJbase.
Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.
CDR delineation
| CDR1 Start | 219 |
| CDR1 End | 248 |
| CDR2 Start | 300 |
| CDR2 End | 320 |
| CDR3 Start | 435 |
Non-Core Regions
| UTR 5' Start | |
| UTR 5' End | |
| L-PART1 Start | 1 |
| L-PART1 End | 46 |
| L_PART1 | ATGGACATACTTTGTTCCACGCTCCTGCTACTGACTGTCCCGTCCT |
| L-PART2 Start | 133 |
| L-PART2 End | 143 |
| L_PART2 | GGGTCTTATCC |
| v_rs_start | 445 |
| v_rs_end | 483 |
| V_HEPTAMER | CACAGAG |
| V_NONAMER | ACAAGAACC |
| Exon 1 Start | |
| Exon 1 End | |
| Exon 2 Start | |
| Exon 2 End | |
| Exon 3 Start | |
| Exon 3 End | |
| Exon 4 Start | |
| Exon 4 End | |
| Exon 5 Start | |
| Exon 5 End | |
| Exon 6 Start | |
| Exon 6 End | |
| Exon 7 Start | |
| Exon 7 End | |
| Exon 8 Start | |
| Exon 8 End | |
| Exon 9 Start | |
| Exon 9 End | |
| UTR 3' Start | |
| UTR 3' End |
Extension
| 3' Extension | |
| 3' start | |
| 3' end | |
| 5' start | |
| 5' end |
Additional Information
| Sequence ID | A02683 |
| Curator | William Lees |
| Curator address | Clareo Biosciences, Louisville, Kentucky, USA |
| Version | 2 |
| Release Date | 2026-05-27 |
| Release Notes | Repeat – had to roll back yesterday’s changes. Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names |
| Locus | IGH |
| Sequence Type | V |
| Gene Subgroup | 2 |
| Gene Designation | 70D |
| Allele Designation | 04 |
| Gene start | 144 |
| Gene end | 444 |
Notes
Notes are added by IARC reviewers.
| Information for this sequence was imported into OGRDB via bulk update with the following notes: Additional information for this sequence was imported into OGRDB via bulk update with the following notes: |
Attachments
History
History logs the times and reasons for the publication of each version of this sequence.
| William Lees 2023-07-10 11:24:36 | Version 1 published Bulk upload of sequences for the AIRR-C Human IG germline sets |
| William Lees 2026-05-27 07:52:07 | Version 2 published Repeat – had to roll back yesterday’s changes. Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names |
Changes from previous version
| v1 | v2 | |
|---|---|---|
| Curator address | Birkbeck College, University of London, Malet Street, London | Clareo Biosciences, Louisville, Kentucky, USA |
| Inference Type | Unrearranged and Rearranged | Genomic Only |
| Subgroup type | none | |
| Full Sequence | ||
| SC Coding Sequence | None | None |
| Gene start | 201 | 144 |
| Gene end | 501 | 444 |
| L-PART1 Start | 1 | |
| L-PART1 End | 46 | |
| L-PART2 Start | 190 | 133 |
| L-PART2 End | 200 | 143 |
| CDR1 Start | 276 | 219 |
| CDR1 End | 305 | 248 |
| CDR2 Start | 357 | 300 |
| CDR2 End | 377 | 320 |
| CDR3 Start | 492 | 435 |
| v_rs_start | 502 | 445 |
| v_rs_end | 540 | 483 |
| Codon Frame | 1 | |
| Paralog Rep | False | True |
| 3' Extension | ||
| 5' Extension | ||
| curational_tags | likely_full-length | none |
| Notes | changed |
Versions
All published versions of this sequence.
| Sequence Name | IMGT Name | Version | Date |
|---|---|---|---|
| IGHV2-70D*04 | IGHV2-70D*04 | 1 | 2023-07-10 |
| IGHV2-70D*04 | IGHV2-70D*04 | 2 | 2026-05-27 |