Details

SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGHV2-70*15
IUIS NameIGHV2-70*15
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityORF
Inference TypeUnrearranged
MappedTrue
Paralogs
Paralog RepFalse

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

AccessionTypeRepositoryStartEndCoding SequenceSC Coding Sequence
MG719339NonlocationalGenBank58540
SRX19354839VGenbank1483

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start219
CDR1 End248
CDR2 Start300
CDR2 End320
CDR3 Start435

Non-Core Regions

UTR 5' Start
UTR 5' End
L-PART1 Start1
L-PART1 End46
L_PART1ATGGACATACTTTGTTCCACGCTCCTGCTACTGACTGTCCCGTCCT
L-PART2 Start133
L-PART2 End143
L_PART2GGGTCTTATCC
v_rs_start445
v_rs_end483
V_HEPTAMERCACAGAG
V_NONAMERACAAGAACC
Exon 1 Start
Exon 1 End
Exon 2 Start
Exon 2 End
Exon 3 Start
Exon 3 End
Exon 4 Start
Exon 4 End
Exon 5 Start
Exon 5 End
Exon 6 Start
Exon 6 End
Exon 7 Start
Exon 7 End
Exon 8 Start
Exon 8 End
Exon 9 Start
Exon 9 End
UTR 3' Start
UTR 3' End

Extension

3' Extension
3' start
3' end
5' start
5' end

Additional Information

Sequence IDA02682
CuratorWilliam Lees
Curator addressClareo Biosciences, Louisville, Kentucky, USA
Version2
Release Date2026-05-27
Release Notes

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

LocusIGH
Sequence TypeV
Gene Subgroup2
Gene Designation70
Allele Designation15
Gene start144
Gene end444

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Information for this sequence was imported into OGRDB via bulk update with the following notes:
Sequence annotation is based on Genbank sample MG719339
VDJbase example haplotype: P1_I57
Mapped by P1_I43 haplotype

Additional information for this sequence was imported into OGRDB via bulk update with the following notes:
Annotation is based on VDJbase record P25_I143_S1 for sample W-86 (Genbank: SRX19354839).

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

William Lees
2023-07-10 11:24:36
Version 1 published

Bulk upload of sequences for the AIRR-C Human IG germline sets

William Lees
2026-05-27 07:52:09
Version 2 published

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

Changes from previous version

v1v2
Curator addressBirkbeck College, University of London, Malet Street, LondonClareo Biosciences, Louisville, Kentucky, USA
Inference TypeUnrearranged and RearrangedUnrearranged
Full Sequence
Gene start201144
Gene end501444
L-PART1 Start1
L-PART1 End46
L-PART2 Start190133
L-PART2 End200143
CDR1 Start276219
CDR1 End305248
CDR2 Start357300
CDR2 End377320
CDR3 Start492435
v_rs_start502445
v_rs_end540483
curational_tagslikely_full-lengthlikely_full_length
Noteschanged

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGHV2-70*15IGHV2-70*1512023-07-10
IGHV2-70*15IGHV2-70*1522026-05-27