Details

SpeciesHomo sapiens
Species subgroup
Subgroup type
Sequence NameIGHV4-4*01
IUIS NameIGHV4-4*01
Alternative names
Affirmation Level1
Full Sequence
Coding Sequence
FunctionalityORF
Inference TypeUnrearranged
MappedTrue
Paralogs
Paralog RepFalse

Un-rearranged Observations

Un-rearranged sequence observations that support this sequence:

AccessionTypeRepositoryStartEndCoding SequenceSC Coding Sequence
HM855944NonlocationalGenBank1332
SRX19354854VGenbank1474

Observations in AIRR-seq Repertoires

Click here to review supporting data in VDJbase.

Clicking the link will take you to VDJbase. Open in a new tab if you want to keep this page open. In VDJbase, click on the count in the Apperances column to see a list of samples in which the sequence was found.

CDR delineation

CDR1 Start215
CDR1 End241
CDR2 Start293
CDR2 End313
CDR3 Start428

Non-Core Regions

UTR 5' Start
UTR 5' End
L-PART1 Start1
L-PART1 End46
L_PART1ATGAAACACCTGTGGTTCTTCCTCCTCCTGGTGGCAGCTCCCAGAT
L-PART2 Start129
L-PART2 End139
L_PART2GGGTCCTGTCT
v_rs_start436
v_rs_end474
V_HEPTAMERCACAGTG
V_NONAMERACACAAACC
Exon 1 Start
Exon 1 End
Exon 2 Start
Exon 2 End
Exon 3 Start
Exon 3 End
Exon 4 Start
Exon 4 End
Exon 5 Start
Exon 5 End
Exon 6 Start
Exon 6 End
Exon 7 Start
Exon 7 End
Exon 8 Start
Exon 8 End
Exon 9 Start
Exon 9 End
UTR 3' Start
UTR 3' End

Extension

3' Extension
3' start
3' end
5' start
5' end

Additional Information

Sequence IDA02983
CuratorWilliam Lees
Curator addressClareo Biosciences, Louisville, Kentucky, USA
Version2
Release Date2026-05-27
Release Notes

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

LocusIGH
Sequence TypeV
Gene Subgroup4
Gene Designation4
Allele Designation01
Gene start140
Gene end435

Acknowledgements

Individuals acknowledged as contributing to this sequence:

No Items

Notes

Notes are added by IARC reviewers.

Information for this sequence was imported into OGRDB via bulk update with the following notes:
Sequence annotation is based on Genbank sample HM855944. Sequence observed in data from Rodriguez et al.
2023 as reported in VDJbase (6 samples). Example subject: P25_I28.

Additional information for this sequence was imported into OGRDB via bulk update with the following notes:
Annotation is based on VDJbase record P25_I64_S1 for sample W-10 (Genbank: SRX19354854).

Attachments

No Items

History

History logs the times and reasons for the publication of each version of this sequence.

William Lees
2023-08-15 12:54:49
Version 1 published

Sequences added following discussion at IARC meeting on 9th August 2023

William Lees
2026-05-27 07:52:06
Version 2 published

Repeat – had to roll back yesterday’s changes.

Added genomic evidence from VDJbase study P25 (PMID37479682), including leaders/RSS for many sequences and additional alleles that currently have IUIS/IMGT names

Changes from previous version

v1v2
Curator addressBirkbeck College, University of London, Malet Street, LondonClareo Biosciences, Louisville, Kentucky, USA
MappedFalseTrue
Inference TypeUnrearranged OnlyUnrearranged
Full Sequence
Gene start47140
Gene end342435
L-PART1 Start1
L-PART1 End46
L-PART2 Start36129
L-PART2 End46139
CDR1 Start122215
CDR1 End148241
CDR2 Start200293
CDR2 End220313
CDR3 Start335428
v_rs_start343436
v_rs_end371474
curational_tagslikely_full-lengthlikely_full_length
Noteschanged

Versions

All published versions of this sequence.

Sequence NameIMGT NameVersionDate
IGHV4-4*01IGHV4-4*0112023-08-15
IGHV4-4*01IGHV4-4*0122026-05-27