Sample | Title |
---|---|
ERS2445847 | Naive B-Cell repertoire |
Record Set | Title |
---|---|
ERX2585603 | Illumina MiSeq paired end sequencing |
Allele name | Sequences | Closest Reference | Closest in Host | NT Diffs (reference) | NT Diffs (host) | NT Substs (reference) | AA Diffs (reference) | AA Substs (reference) | Sequence |
---|---|---|---|---|---|---|---|---|---|
IGHV3-9*01_T307C | 453 | IGHV3-9*01 | IGHV3-9*01 | 1 | 1 | T307C | 1 | Y103H | |
IGHV4-61*02_A234G | 613 | IGHV4-61*02 | IGHV4-4*07 | 1 | 4 | A234G | 1 | I78M | |
IGHV5-51*01_C45G | 422 | IGHV5-51*03 | IGHV1-46*03 | 0 | 80 | -319C,-320A | 0 |
Allele name | Sequences | Unmutated Seqs | Unmutated % within allele | Unmutated UMIs | Allelic % | Total unmutated population (%) | Unique CDR3s | Unique CDR3s with unmutated | Haplotyping Gene | Haplotyping Ratio | Sequence |
---|---|---|---|---|---|---|---|---|---|---|---|
IGHV1-2*02 | 604 | 502 | 83.11 | 100.00 | 2.07 | 578 | 491 | IGHJ6 | 6:94 | ||
IGHV1-3*01 | 374 | 333 | 89.04 | 100.00 | 1.37 | 360 | 327 | IGHJ6 | 100:0 | ||
IGHV1-8*01 | 1696 | 1547 | 91.21 | 100.00 | 6.38 | 1636 | 1515 | IGHJ6 | 72:28 | ||
IGHV1-18*01 | 1023 | 908 | 88.76 | 100.00 | 3.75 | 1000 | 903 | IGHJ6 | 49:51 | ||
IGHV1-24*01 | 230 | 203 | 88.26 | 100.00 | 0.84 | 220 | 197 | IGHJ6 | 67:33 | ||
IGHV1-45*02 | 2 | 2 | 100.00 | 100.00 | 0.01 | 2 | 2 | IGHJ6 | |||
IGHV1-46*03 | 324 | 285 | 87.96 | 100.00 | 1.18 | 318 | 283 | IGHJ6 | 66:34 | ||
IGHV1-58*01 | 63 | 56 | 88.89 | 74.00 | 0.23 | 62 | 56 | IGHJ6 | 100:0 | ||
IGHV1-58*02 | 22 | 21 | 95.45 | 26.00 | 0.09 | 21 | 20 | IGHJ6 | 0:100 | ||
IGHV1-69*04 | 844 | 746 | 88.39 | 100.00 | 3.08 | 813 | 729 | IGHJ6 | 99:1 | ||
IGHV2-5*01 | 2019 | 1822 | 90.24 | 100.00 | 7.52 | 1961 | 1795 | IGHJ6 | 88:12 | ||
IGHV2-26*01 | 261 | 240 | 91.95 | 100.00 | 0.99 | 258 | 239 | IGHJ6 | 31:69 | ||
IGHV2-70*01 | 52 | 42 | 80.77 | 29.00 | 0.17 | 51 | 41 | IGHJ6 | 0:100 | ||
IGHV2-70*15 | 129 | 120 | 93.02 | 71.00 | 0.50 | 128 | 120 | IGHJ6 | 100:0 | ||
IGHV3-7*01 | 1427 | 1191 | 83.46 | 100.00 | 4.91 | 1390 | 1173 | IGHJ6 | 74:26 | ||
IGHV3-9*01 | 797 | 667 | 83.69 | 64.00 | 2.75 | 762 | 654 | IGHJ6 | 1:99 | ||
IGHV3-9*01_T307C | 453 | 378 | 83.44 | 36.00 | 1.56 | 437 | 373 | IGHJ6 | 100:0 | ||
IGHV3-11*01 | 1392 | 1170 | 84.05 | 100.00 | 4.83 | 1336 | 1151 | IGHJ6 | 71:29 | ||
IGHV3-13*01 | 189 | 165 | 87.30 | 100.00 | 0.68 | 184 | 164 | IGHJ6 | 66:34 | ||
IGHV3-15*01 | 865 | 747 | 86.36 | 100.00 | 3.08 | 836 | 738 | IGHJ6 | 49:51 | ||
IGHV3-20*01 | 104 | 86 | 82.69 | 100.00 | 0.35 | 99 | 83 | IGHJ6 | 39:61 | ||
IGHV3-21*01 | 1564 | 1352 | 86.45 | 100.00 | 5.58 | 1508 | 1332 | IGHJ6 | 60:40 | ||
IGHV3-30-3*01 | 735 | 606 | 82.45 | 100.00 | 2.50 | 701 | 592 | IGHJ6 | 1:99 | ||
IGHV3-33*01 | 1779 | 1505 | 84.60 | 100.00 | 6.21 | 1710 | 1475 | IGHJ6 | 63:37 | ||
IGHV3-41*02 | 1 | 0 | 0.00 | 100.00 | 0.00 | 1 | 0 | IGHJ6 | |||
IGHV3-43*01 | 78 | 71 | 91.03 | 100.00 | 0.29 | 77 | 71 | IGHJ6 | 50:50 | ||
IGHV3-48*01 | 684 | 572 | 83.63 | 100.00 | 2.36 | 662 | 563 | IGHJ6 | 62:38 | ||
IGHV3-49*03 | 314 | 269 | 85.67 | 100.00 | 1.11 | 302 | 264 | IGHJ6 | 48:52 | ||
IGHV3-53*02 | 188 | 154 | 81.91 | 100.00 | 0.64 | 178 | 153 | IGHJ6 | 53:47 | ||
IGHV3-64*02 | 8 | 6 | 75.00 | 100.00 | 0.02 | 7 | 6 | IGHJ6 | |||
IGHV3-66*01 | 410 | 362 | 88.29 | 100.00 | 1.49 | 388 | 356 | IGHJ6 | 100:0 | ||
IGHV3-72*01 | 59 | 49 | 83.05 | 100.00 | 0.20 | 56 | 47 | IGHJ6 | 48:52 | ||
IGHV3-73*01 | 57 | 44 | 77.19 | 48.00 | 0.18 | 57 | 44 | IGHJ6 | 100:0 | ||
IGHV3-73*02 | 63 | 54 | 85.71 | 52.00 | 0.22 | 63 | 54 | IGHJ6 | 0:100 | ||
IGHV3-74*01 | 267 | 229 | 85.77 | 100.00 | 0.94 | 258 | 226 | IGHJ6 | 75:25 | ||
IGHV4-4*07 | 295 | 251 | 85.08 | 100.00 | 1.04 | 286 | 249 | IGHJ6 | 2:98 | ||
IGHV4-28*01 | 1 | 1 | 100.00 | 50.00 | 0.00 | 1 | 1 | IGHJ6 | |||
IGHV4-28*03 | 1 | 1 | 100.00 | 50.00 | 0.00 | 1 | 1 | IGHJ6 | |||
IGHV4-30-2*01 | 242 | 217 | 89.67 | 100.00 | 0.90 | 239 | 216 | IGHJ6 | 37:63 | ||
IGHV4-30-4*01 | 218 | 191 | 87.61 | 100.00 | 0.79 | 212 | 188 | IGHJ6 | 2:98 | ||
IGHV4-31*03 | 1095 | 976 | 89.13 | 100.00 | 4.03 | 1060 | 962 | IGHJ6 | 41:59 | ||
IGHV4-34*01 | 2124 | 1878 | 88.42 | 100.00 | 7.75 | 2036 | 1834 | IGHJ6 | 46:54 | ||
IGHV4-39*01 | 2264 | 1969 | 86.97 | 100.00 | 8.12 | 2154 | 1920 | IGHJ6 | 47:53 | ||
IGHV4-59*01 | 728 | 639 | 87.77 | 100.00 | 2.64 | 717 | 636 | IGHJ6 | 36:64 | ||
IGHV4-61*01 | 120 | 108 | 90.00 | 16.00 | 0.45 | 118 | 107 | IGHJ6 | 100:0 | ||
IGHV4-61*02_A234G | 613 | 530 | 86.46 | 84.00 | 2.19 | 600 | 528 | IGHJ6 | 0:100 | ||
IGHV5-51*01_C45G | 422 | 376 | 89.10 | 100.00 | 1.55 | 408 | 369 | IGHJ6 | 83:17 | ||
IGHV6-1*01 | 189 | 173 | 91.53 | 100.00 | 0.71 | 187 | 172 | IGHJ6 | 64:36 | ||
IGHV7-4-1*02 | 493 | 424 | 86.00 | 100.00 | 1.75 | 478 | 416 | IGHJ6 | 98:2 | ||
Totals | 27882 | 24238 | 86.93 | 1307:-1207 |