Genotype 'LP23810' (Submission S00008)
| Sample | Title |
|---|---|
| SAMN06821265 | LP23810-IgM-RACE1 |
| SAMN06821266 | LP23810-IgM-RACE2 |
| Record Set | Title |
|---|---|
| SRR5471273 | IGH variable regions sequenced from peripheral B cells of normal donor LP23810 using an IgM constant region primer and 5’ RACE |
| SRR5471272 | IGH variable regions sequenced from peripheral B cells of normal donor LP23810 using an IgM constant region primer and 5’ RACE |
Allele names in italic are not listed in the reference set. Allele names in bold are put forward in the submission for consideration as inferred sequences.
A cross in the Sequence column indicates that the sequence listed in the genotype does not match the sequence of the corresponding allele in the reference set.
An information icon in the Sequence column alerts you to other information on this sequence - hover over for details.
Novel Alleles
Allele name | Sequences | Closest Reference | Closest in Host | NT Diffs (reference) | NT Diffs (host) | NT Substs (reference) | AA Diffs (reference) | AA Substs (reference) | Sequence |
|---|---|---|---|---|---|---|---|---|---|
| IGHV1-58*01+G29A | 178 | IGHV1-58*01 | IGHV1-58*01 | 1 | G30A | 0 | |||
| IGHV3-21*01+T52C | 9 | IGHV3-21*01 | IGHV3-21*01 | 1 | T56C | 1 | L19P | ||
| IGHV3-43*01+A96G.C197T.A261G | 146 | IGHV3-43*01 | IGHV3-9*01 | 3 | A112G,C219T,A286G | 2 | T38A,T96A | ||
| IGHV3-64*05+A188C.G240C | 281 | IGHV3-64*05 | IGHV3-23*04 | 2 | A207C,G265C | 1 | V89L | ||
| IGHV4-38-2*02+G76A.T136G.G169C | 1912 | IGHV4-38-2*02 | IGHV4-38-2*01 | 3 | G80A,T149G,G191C | 3 | G27D,L50R,S64T |
Genotype
Allele name | Sequences | Unmutated Seqs | Unmutated % within allele | Unmutated UMIs | Allelic % | Total unmutated population (%) | Unique CDR3s | Unique CDR3s with unmutated | Haplotyping Gene | Haplotyping Ratio | Sequence |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IGHV1-18*01 | 1946 | 1314 | 67.52 | 100.00 | 2.00 | 952 | Haplotyping not possible | ||||
| IGHV1-2*02 | 9951 | 5949 | 59.78 | 100.00 | 9.00 | 5049 | Haplotyping not possible | ||||
| IGHV1-24*01 | 5034 | 3942 | 78.31 | 100.00 | 6.00 | 2261 | Haplotyping not possible | ||||
| IGHV1-46*01 | 1007 | 572 | 56.80 | 100.00 | 0.00 | 477 | Haplotyping not possible | ||||
| IGHV1-58*01 | 214 | 160 | 74.77 | 55.00 | 0.00 | 100 | Haplotyping not possible | ||||
| IGHV1-58*01+G29A | 178 | 127 | 71.35 | 44.00 | 0.00 | 83 | Haplotyping not possible | ||||
| IGHV1-69*01 | 10270 | 7586 | 73.87 | 100.00 | 12.00 | 4996 | Haplotyping not possible | ||||
| IGHV1-8*01 | 1829 | 942 | 51.50 | 100.00 | 1.00 | 781 | Haplotyping not possible | ||||
| IGHV2-26*01 | 248 | 153 | 61.69 | 100.00 | 0.00 | 167 | Haplotyping not possible | ||||
| IGHV2-5*02 | 956 | 463 | 48.43 | 100.00 | 0.00 | 599 | Haplotyping not possible | ||||
| IGHV2-70*01 | 132 | 86 | 65.15 | 100.00 | 0.00 | 93 | Haplotyping not possible | ||||
| IGHV3-11*01 | 239 | 142 | 59.41 | 70.00 | 0.00 | 134 | Haplotyping not possible | ||||
| IGHV3-11*06 | 98 | 59 | 60.20 | 29.00 | 0.00 | 57 | Haplotyping not possible | ||||
| IGHV3-13*01 | 298 | 123 | 41.28 | 100.00 | 0.00 | 150 | Haplotyping not possible | ||||
| IGHV3-15*01 | 1286 | 653 | 50.78 | 100.00 | 1.00 | 781 | Haplotyping not possible | ||||
| IGHV3-20*01 | 116 | 63 | 54.31 | 100.00 | 0.00 | 73 | Haplotyping not possible | ||||
| IGHV3-21*01 | 4069 | 2442 | 60.01 | 100.00 | 3.00 | 2070 | Haplotyping not possible | ||||
| IGHV3-21*01+T52C | 9 | 0 | 0.00 | 0.00 | 0.00 | 7 | Haplotyping not possible | ||||
| IGHV3-23*01 | 8499 | 3203 | 37.69 | 83.00 | 5.00 | 4662 | Haplotyping not possible | ||||
| IGHV3-23*04 | 1247 | 616 | 49.40 | 16.00 | 0.00 | 823 | Haplotyping not possible | ||||
| IGHV3-30*01 | 203 | 98 | 48.28 | 22.00 | 0.00 | 131 | Haplotyping not possible | ||||
| IGHV3-30*03 | 4810 | 338 | 7.03 | 77.00 | 0.00 | 2626 | Haplotyping not possible | ||||
| IGHV3-33*01 | 3650 | 1983 | 54.33 | 100.00 | 3.00 | 1839 | Haplotyping not possible | ||||
| IGHV3-43*01+A96G.C197T.A261G | 146 | 100 | 68.49 | 100.00 | 0.00 | 79 | Haplotyping not possible | ||||
| IGHV3-48*03 | 4168 | 2103 | 50.46 | 100.00 | 3.00 | 2105 | Haplotyping not possible | ||||
| IGHV3-49*04 | 712 | 401 | 56.32 | 100.00 | 0.00 | 403 | Haplotyping not possible | ||||
| IGHV3-53*01 | 3124 | 1321 | 42.29 | 78.00 | 2.00 | 1733 | Haplotyping not possible | ||||
| IGHV3-53*02 | 634 | 372 | 58.68 | 21.00 | 0.00 | 402 | Haplotyping not possible | ||||
| IGHV3-64*05+A188C.G240C | 281 | 110 | 39.15 | 100.00 | 0.00 | 147 | Haplotyping not possible | ||||
| IGHV3-7*01 | 4336 | 1196 | 27.58 | 100.00 | 1.00 | 1745 | Haplotyping not possible | ||||
| IGHV3-72*01 | 280 | 37 | 13.21 | 100.00 | 0.00 | 122 | Haplotyping not possible | ||||
| IGHV3-73*02 | 367 | 157 | 42.78 | 100.00 | 0.00 | 208 | Haplotyping not possible | ||||
| IGHV3-74*01 | 2076 | 610 | 29.38 | 100.00 | 0.00 | 840 | Haplotyping not possible | ||||
| IGHV3-9*01 | 1202 | 774 | 64.39 | 100.00 | 1.00 | 597 | Haplotyping not possible | ||||
| IGHV4-31*01 | 188 | 96 | 51.06 | 12.00 | 0.00 | 94 | Haplotyping not possible | ||||
| IGHV4-31*03 | 1210 | 695 | 57.44 | 87.00 | 1.00 | 592 | Haplotyping not possible | ||||
| IGHV4-34*01 | 22377 | 12998 | 58.09 | 100.00 | 21.00 | 13572 | Haplotyping not possible | ||||
| IGHV4-38-2*01 | 9520 | 4870 | 51.16 | 100.00 | 7.00 | 5216 | Haplotyping not possible | ||||
| IGHV4-38-2*02+G76A.T136G.G169C | 1912 | 0 | 0.00 | 0.00 | 0.00 | 1601 | Haplotyping not possible | ||||
| IGHV4-4*07 | 3243 | 1522 | 46.93 | 100.00 | 2.00 | 1726 | Haplotyping not possible | ||||
| IGHV4-59*01 | 2122 | 1033 | 48.68 | 100.00 | 1.00 | 1167 | Haplotyping not possible | ||||
| IGHV4-61*01 | 866 | 367 | 42.38 | 100.00 | 0.00 | 450 | Haplotyping not possible | ||||
| IGHV5-10-1*03 | 435 | 280 | 64.37 | 100.00 | 0.00 | 189 | Haplotyping not possible | ||||
| IGHV5-51*01 | 2180 | 1274 | 58.44 | 100.00 | 2.00 | 861 | Haplotyping not possible | ||||
| IGHV6-1*01 | 1299 | 395 | 30.41 | 100.00 | 0.00 | 537 | Haplotyping not possible | ||||
| Totals | 118967 | 61725 | 51.88 |