Genotype 'LP23810' (Submission S00008)
NCBI Information
| Sample | Title |
|---|---|
| SAMN06821265 | LP23810-IgM-RACE1 |
| SAMN06821266 | LP23810-IgM-RACE2 |
| Record Set | Title |
|---|---|
| SRR5471273 | IGH variable regions sequenced from peripheral B cells of normal donor LP23810 using an IgM constant region primer and 5’ RACE |
| SRR5471272 | IGH variable regions sequenced from peripheral B cells of normal donor LP23810 using an IgM constant region primer and 5’ RACE |
Legend:
- Allele names in italic are not listed in the reference set.
- Allele names in bold are put forward in the submission for consideration as inferred sequences.
- A cross in the Sequence column indicates that the sequence listed in the genotype does not match the sequence of the corresponding allele in the reference set.
- An information icon in the Sequence column alerts you to other information on this sequence - hover over for details.
Novel Alleles
Allele name | Sequences | Closest Reference | Closest in Host | NT Diffs (reference) | NT Diffs (host) | NT Substs (reference) | AA Diffs (reference) | AA Substs (reference) | Sequence |
|---|---|---|---|---|---|---|---|---|---|
| IGHV1-58*01+G29A | 178 | IGHV1-58*01 | IGHV1-58*01 | 1 | G30A | 0 | |||
| IGHV3-21*01+T52C | 9 | IGHV3-21*01 | IGHV3-21*01 | 1 | T56C | 1 | L19P | ||
| IGHV3-43*01+A96G.C197T.A261G | 146 | IGHV3-43*01 | IGHV3-9*01 | 3 | A112G,C219T,A286G | 2 | T38A,T96A | ||
| IGHV3-64*05+A188C.G240C | 281 | IGHV3-64*05 | IGHV3-23*04 | 2 | A207C,G265C | 1 | V89L | ||
| IGHV4-38-2*02+G76A.T136G.G169C | 1912 | IGHV4-38-2*02 | IGHV4-38-2*01 | 3 | G80A,T149G,G191C | 3 | G27D,L50R,S64T |
Genotype
Allele name | Sequences | Unmutated Seqs | Unmutated % within allele | Unmutated UMIs | Allelic % | Total unmutated population (%) | Unique CDR3s | Unique CDR3s with unmutated | Haplotyping Gene | Haplotyping Ratio | Sequence |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IGHV1-18*01 | 1946 | 1314 | 67.52 | 100.00 | 2.00 | 952 | Haplotyping not possible | ||||
| IGHV1-2*02 | 9951 | 5949 | 59.78 | 100.00 | 9.00 | 5049 | Haplotyping not possible | ||||
| IGHV1-24*01 | 5034 | 3942 | 78.31 | 100.00 | 6.00 | 2261 | Haplotyping not possible | ||||
| IGHV1-46*01 | 1007 | 572 | 56.80 | 100.00 | 0.00 | 477 | Haplotyping not possible | ||||
| IGHV1-58*01 | 214 | 160 | 74.77 | 55.00 | 0.00 | 100 | Haplotyping not possible | ||||
| IGHV1-58*01+G29A | 178 | 127 | 71.35 | 44.00 | 0.00 | 83 | Haplotyping not possible | ||||
| IGHV1-69*01 | 10270 | 7586 | 73.87 | 100.00 | 12.00 | 4996 | Haplotyping not possible | ||||
| IGHV1-8*01 | 1829 | 942 | 51.50 | 100.00 | 1.00 | 781 | Haplotyping not possible | ||||
| IGHV2-26*01 | 248 | 153 | 61.69 | 100.00 | 0.00 | 167 | Haplotyping not possible | ||||
| IGHV2-5*02 | 956 | 463 | 48.43 | 100.00 | 0.00 | 599 | Haplotyping not possible | ||||
| IGHV2-70*01 | 132 | 86 | 65.15 | 100.00 | 0.00 | 93 | Haplotyping not possible | ||||
| IGHV3-11*01 | 239 | 142 | 59.41 | 70.00 | 0.00 | 134 | Haplotyping not possible | ||||
| IGHV3-11*06 | 98 | 59 | 60.20 | 29.00 | 0.00 | 57 | Haplotyping not possible | ||||
| IGHV3-13*01 | 298 | 123 | 41.28 | 100.00 | 0.00 | 150 | Haplotyping not possible | ||||
| IGHV3-15*01 | 1286 | 653 | 50.78 | 100.00 | 1.00 | 781 | Haplotyping not possible | ||||
| IGHV3-20*01 | 116 | 63 | 54.31 | 100.00 | 0.00 | 73 | Haplotyping not possible | ||||
| IGHV3-21*01 | 4069 | 2442 | 60.01 | 100.00 | 3.00 | 2070 | Haplotyping not possible | ||||
| IGHV3-21*01+T52C | 9 | 0 | 0.00 | 0.00 | 0.00 | 7 | Haplotyping not possible | ||||
| IGHV3-23*01 | 8499 | 3203 | 37.69 | 83.00 | 5.00 | 4662 | Haplotyping not possible | ||||
| IGHV3-23*04 | 1247 | 616 | 49.40 | 16.00 | 0.00 | 823 | Haplotyping not possible | ||||
| IGHV3-30*01 | 203 | 98 | 48.28 | 22.00 | 0.00 | 131 | Haplotyping not possible | ||||
| IGHV3-30*03 | 4810 | 338 | 7.03 | 77.00 | 0.00 | 2626 | Haplotyping not possible | ||||
| IGHV3-33*01 | 3650 | 1983 | 54.33 | 100.00 | 3.00 | 1839 | Haplotyping not possible | ||||
| IGHV3-43*01+A96G.C197T.A261G | 146 | 100 | 68.49 | 100.00 | 0.00 | 79 | Haplotyping not possible | ||||
| IGHV3-48*03 | 4168 | 2103 | 50.46 | 100.00 | 3.00 | 2105 | Haplotyping not possible | ||||
| IGHV3-49*04 | 712 | 401 | 56.32 | 100.00 | 0.00 | 403 | Haplotyping not possible | ||||
| IGHV3-53*01 | 3124 | 1321 | 42.29 | 78.00 | 2.00 | 1733 | Haplotyping not possible | ||||
| IGHV3-53*02 | 634 | 372 | 58.68 | 21.00 | 0.00 | 402 | Haplotyping not possible | ||||
| IGHV3-64*05+A188C.G240C | 281 | 110 | 39.15 | 100.00 | 0.00 | 147 | Haplotyping not possible | ||||
| IGHV3-7*01 | 4336 | 1196 | 27.58 | 100.00 | 1.00 | 1745 | Haplotyping not possible | ||||
| IGHV3-72*01 | 280 | 37 | 13.21 | 100.00 | 0.00 | 122 | Haplotyping not possible | ||||
| IGHV3-73*02 | 367 | 157 | 42.78 | 100.00 | 0.00 | 208 | Haplotyping not possible | ||||
| IGHV3-74*01 | 2076 | 610 | 29.38 | 100.00 | 0.00 | 840 | Haplotyping not possible | ||||
| IGHV3-9*01 | 1202 | 774 | 64.39 | 100.00 | 1.00 | 597 | Haplotyping not possible | ||||
| IGHV4-31*01 | 188 | 96 | 51.06 | 12.00 | 0.00 | 94 | Haplotyping not possible | ||||
| IGHV4-31*03 | 1210 | 695 | 57.44 | 87.00 | 1.00 | 592 | Haplotyping not possible | ||||
| IGHV4-34*01 | 22377 | 12998 | 58.09 | 100.00 | 21.00 | 13572 | Haplotyping not possible | ||||
| IGHV4-38-2*01 | 9520 | 4870 | 51.16 | 100.00 | 7.00 | 5216 | Haplotyping not possible | ||||
| IGHV4-38-2*02+G76A.T136G.G169C | 1912 | 0 | 0.00 | 0.00 | 0.00 | 1601 | Haplotyping not possible | ||||
| IGHV4-4*07 | 3243 | 1522 | 46.93 | 100.00 | 2.00 | 1726 | Haplotyping not possible | ||||
| IGHV4-59*01 | 2122 | 1033 | 48.68 | 100.00 | 1.00 | 1167 | Haplotyping not possible | ||||
| IGHV4-61*01 | 866 | 367 | 42.38 | 100.00 | 0.00 | 450 | Haplotyping not possible | ||||
| IGHV5-10-1*03 | 435 | 280 | 64.37 | 100.00 | 0.00 | 189 | Haplotyping not possible | ||||
| IGHV5-51*01 | 2180 | 1274 | 58.44 | 100.00 | 2.00 | 861 | Haplotyping not possible | ||||
| IGHV6-1*01 | 1299 | 395 | 30.41 | 100.00 | 0.00 | 537 | Haplotyping not possible | ||||
| Totals | 118967 | 61725 | 51.88 |