Genotype 'LP08248' (Submission S00007)
NCBI Information
| Sample | Title |
|---|---|
| SAMN06821255 | LP08248-IgM-RACE2 |
| SAMN06821254 | LP08248-IgM-RACE1 |
| Record Set | Title |
|---|---|
| SRR5471283 | IGH variable regions sequenced from peripheral B cells of normal donor LP08248 using an IgM constant region primer and 5’ RACE |
| SRR5471284 | IGH variable regions sequenced from peripheral B cells of normal donor LP08248 using an IgM constant region primer and 5’ RACE |
Legend:
- Allele names in italic are not listed in the reference set.
- Allele names in bold are put forward in the submission for consideration as inferred sequences.
- A cross in the Sequence column indicates that the sequence listed in the genotype does not match the sequence of the corresponding allele in the reference set.
- An information icon in the Sequence column alerts you to other information on this sequence - hover over for details.
Novel Alleles
Allele name | Sequences | Closest Reference | Closest in Host | NT Diffs (reference) | NT Diffs (host) | NT Substs (reference) | AA Diffs (reference) | AA Substs (reference) | Sequence |
|---|---|---|---|---|---|---|---|---|---|
| IGHV1-8*02+G209T | 1332 | IGHV1-8*02 | IGHV1-2*02 | 1 | G231T | 1 | M78I | ||
| IGHV2-70*11+G1A | 435 | IGHV2-70*11 | IGHV2-5*01 | 1 | G2A | 1 | R1Q | ||
| IGHV3-23*04+C148T.T152C.C234G | 45 | IGHV3-23*04 | IGHV3-23*04 | 3 | C164T,T165C,C259G | 2 | A55V,L87V | ||
| IGHV3-43*01+A96G.A173C | 142 | IGHV3-43*01 | IGHV3-43*01 | 2 | A112G,A192C | 1 | T38A | ||
| IGHV4-31*03+A66G | 812 | IGHV4-31*03 | IGHV4-30-4*07 | 1 | A70G | 1 | T24A | ||
| IGHV4-34*01+G116A | 4549 | IGHV4-34*01 | IGHV4-34*01 | 1 | G129A | 0 | |||
| IGHV4-34*01+G270A | 977 | IGHV4-34*01 | IGHV4-34*01 | 1 | G298A | 1 | A100T | ||
| IGHV4-39*07+C19T | 15309 | IGHV4-39*07 | IGHV4-39*07 | 1 | C20T | 1 | S7L | ||
| IGHV4-39*07+T99A.T177A.G216A | 8 | IGHV4-39*07 | IGHV4-39*07 | 3 | T109A,T196A,G238A | 3 | Y37N,Y66N,V80I | ||
| IGHV4-59*01+C114T | 1 | IGHV4-59*01 | IGHV4-59*01 | 1 | C130T | 1 | Q44* | ||
| IGHV4-59*01+T260C | 1515 | IGHV4-59*01 | IGHV4-59*01 | 1 | T285C | 0 | |||
| IGHV5-51*03+C203T | 1128 | IGHV5-51*03 | IGHV5-51*03 | 1 | C225T | 0 |
Genotype
Allele name | Sequences | Unmutated Seqs | Unmutated % within allele | Unmutated UMIs | Allelic % | Total unmutated population (%) | Unique CDR3s | Unique CDR3s with unmutated | Haplotyping Gene | Haplotyping Ratio | Sequence |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IGHV1-18*01 | 1786 | 788 | 44.12 | 100.00 | 4.00 | 878 | Haplotyping not possible | ||||
| IGHV1-2*02 | 3535 | 1007 | 28.49 | 100.00 | 5.00 | 1458 | Haplotyping not possible | ||||
| IGHV1-24*01 | 715 | 433 | 60.56 | 100.00 | 2.00 | 271 | Haplotyping not possible | ||||
| IGHV1-46*01 | 1703 | 396 | 23.25 | 100.00 | 2.00 | 555 | Haplotyping not possible | ||||
| IGHV1-58*02 | 138 | 77 | 55.80 | 100.00 | 0.00 | 65 | Haplotyping not possible | ||||
| IGHV1-69*10 | 528 | 251 | 47.54 | 19.00 | 1.00 | 209 | Haplotyping not possible | ||||
| IGHV1-69*13 | 2475 | 1029 | 41.58 | 80.00 | 5.00 | 1151 | Haplotyping not possible | ||||
| IGHV1-69-2*01 | 285 | 159 | 55.79 | 100.00 | 0.00 | 110 | Haplotyping not possible | ||||
| IGHV1-8*02+G209T | 1332 | 603 | 45.27 | 100.00 | 3.00 | 544 | Haplotyping not possible | ||||
| IGHV2-26*01 | 229 | 102 | 44.54 | 100.00 | 0.00 | 113 | Haplotyping not possible | ||||
| IGHV2-5*01 | 1142 | 430 | 37.65 | 100.00 | 2.00 | 595 | Haplotyping not possible | ||||
| IGHV2-70*11+G1A | 435 | 54 | 12.41 | 100.00 | 0.00 | 261 | Haplotyping not possible | ||||
| IGHV3-11*04 | 122 | 27 | 22.13 | 100.00 | 0.00 | 75 | Haplotyping not possible | ||||
| IGHV3-15*01 | 510 | 122 | 23.92 | 100.00 | 0.00 | 257 | Haplotyping not possible | ||||
| IGHV3-20*01 | 103 | 26 | 25.24 | 100.00 | 0.00 | 44 | Haplotyping not possible | ||||
| IGHV3-21*01 | 1432 | 435 | 30.38 | 100.00 | 2.00 | 626 | Haplotyping not possible | ||||
| IGHV3-23*01 | 1310 | 303 | 23.13 | 29.00 | 1.00 | 742 | Haplotyping not possible | ||||
| IGHV3-23*04 | 4137 | 707 | 17.09 | 69.00 | 3.00 | 2138 | Haplotyping not possible | ||||
| IGHV3-23*04+C148T.T152C.C234G | 45 | 3 | 6.67 | 0.00 | 0.00 | 14 | Haplotyping not possible | ||||
| IGHV3-30*04 | 1744 | 589 | 33.77 | 100.00 | 3.00 | 843 | Haplotyping not possible | ||||
| IGHV3-33*01 | 2763 | 547 | 19.80 | 100.00 | 2.00 | 1185 | Haplotyping not possible | ||||
| IGHV3-43*01 | 71 | 19 | 26.76 | 100.00 | 0.00 | 33 | Haplotyping not possible | ||||
| IGHV3-43*01+A96G.A173C | 142 | 0 | 0.00 | 0.00 | 0.00 | 61 | Haplotyping not possible | ||||
| IGHV3-48*03 | 2000 | 490 | 24.50 | 100.00 | 2.00 | 1036 | Haplotyping not possible | ||||
| IGHV3-49*04 | 416 | 99 | 23.80 | 100.00 | 0.00 | 213 | Haplotyping not possible | ||||
| IGHV3-53*01 | 2640 | 423 | 16.02 | 100.00 | 2.00 | 1091 | Haplotyping not possible | ||||
| IGHV3-64*01 | 238 | 64 | 26.89 | 100.00 | 0.00 | 98 | Haplotyping not possible | ||||
| IGHV3-66*01 | 749 | 217 | 28.97 | 100.00 | 1.00 | 378 | Haplotyping not possible | ||||
| IGHV3-7*01 | 2312 | 394 | 17.04 | 100.00 | 2.00 | 1090 | Haplotyping not possible | ||||
| IGHV3-72*01 | 136 | 5 | 3.68 | 100.00 | 0.00 | 65 | Haplotyping not possible | ||||
| IGHV3-73*02 | 121 | 16 | 13.22 | 100.00 | 0.00 | 52 | Haplotyping not possible | ||||
| IGHV3-74*01 | 1509 | 119 | 7.89 | 100.00 | 0.00 | 527 | Haplotyping not possible | ||||
| IGHV3-9*03 | 447 | 143 | 31.99 | 100.00 | 0.00 | 176 | Haplotyping not possible | ||||
| IGHV4-30-2*01 | 1281 | 567 | 44.26 | 100.00 | 2.00 | 567 | Haplotyping not possible | ||||
| IGHV4-30-4*07 | 599 | 220 | 36.73 | 100.00 | 1.00 | 291 | Haplotyping not possible | ||||
| IGHV4-31*03+A66G | 812 | 293 | 36.08 | 100.00 | 1.00 | 383 | Haplotyping not possible | ||||
| IGHV4-34*01 | 3221 | 865 | 26.86 | 98.00 | 4.00 | 1446 | Haplotyping not possible | ||||
| IGHV4-34*01+G116A | 4549 | 6 | 0.13 | 0.00 | 0.00 | 2285 | Haplotyping not possible | ||||
| IGHV4-34*01+G270A | 977 | 4 | 0.41 | 0.00 | 0.00 | 797 | Haplotyping not possible | ||||
| IGHV4-38-2*02 | 5558 | 1720 | 30.95 | 100.00 | 9.00 | 2216 | Haplotyping not possible | ||||
| IGHV4-39*07 | 3855 | 829 | 21.50 | 98.00 | 4.00 | 1520 | Haplotyping not possible | ||||
| IGHV4-39*07+C19T | 15309 | 11 | 0.07 | 1.00 | 0.00 | 6756 | Haplotyping not possible | ||||
| IGHV4-39*07+T99A.T177A.G216A | 8 | 0 | 0.00 | 0.00 | 0.00 | 2 | Haplotyping not possible | ||||
| IGHV4-4*02 | 1541 | 397 | 25.76 | 100.00 | 2.00 | 674 | Haplotyping not possible | ||||
| IGHV4-59*01 | 5397 | 1618 | 29.98 | 82.00 | 8.00 | 2437 | Haplotyping not possible | ||||
| IGHV4-59*01+C114T | 1 | 0 | 0.00 | 0.00 | 0.00 | 1 | Haplotyping not possible | ||||
| IGHV4-59*01+T260C | 1515 | 341 | 22.51 | 17.00 | 1.00 | 559 | Haplotyping not possible | ||||
| IGHV4-61*02 | 4903 | 1363 | 27.80 | 100.00 | 7.00 | 2198 | Haplotyping not possible | ||||
| IGHV4-61*08 | 71 | 0 | 0.00 | 0.00 | 0.00 | 39 | Haplotyping not possible | ||||
| IGHV5-51*03 | 1539 | 357 | 23.20 | 54.00 | 1.00 | 650 | Haplotyping not possible | ||||
| IGHV5-51*03+C203T | 1128 | 304 | 26.95 | 45.00 | 1.00 | 475 | Haplotyping not possible | ||||
| IGHV6-1*01 | 677 | 68 | 10.04 | 100.00 | 0.00 | 257 | Haplotyping not possible | ||||
| Totals | 90191 | 19040 | 21.11 |