{ "GermlineSet": [ { "germline_set_id": "OGRDB:G00054", "author": "William Lees", "lab_name": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "acknowledgements": null, "release_version": 1, "release_description": "First release", "release_date": "2022-05-31", "germline_set_name": "IGKJ (all strains)", "germline_set_ref": "OGRDB:IGKJ (all strains).1", "pub_ids": null, "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "locus": "IGK", "allele_descriptions": [ { "allele_description_id": "OGRDB:A02500", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-4JXG.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-4JXG*00", "sequence": "GTGGACGTTCGGTGGAGGCACCAAGCTGGAAATCAAAC", "coding_sequence": "GTGGACGTTCGGTGGAGGCACCAAGCTGGAAATCAAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ1*01" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 38, "j_codon_frame": 2, "j_cdr3_end": 8, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null }, { "allele_description_id": "OGRDB:A02506", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-5NUZ.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-5NUZ*00", "sequence": "AACCACATTCAGTGATGGGACCAGACTGGAAATAAAAC", "coding_sequence": "AACCACATTCAGTGATGGGACCAGACTGGAAATAAAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ3*02" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 38, "j_codon_frame": 2, "j_cdr3_end": 8, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": "Missing canonical GxG motif and not observed in repertoires in Kos et al.\r\n\r\naacc aca ttc agt gat ggg acc aga ctg gaa ata aaa \r\n T T F S D G T R L E I K\r\n", "curational_tags": [ null ] }, { "allele_description_id": "OGRDB:A02510", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-ABRI.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-ABRI*00", "sequence": "TGTACACGTTCGGATCGGGGACCAAGCTGGAAATAAAAC", "coding_sequence": "TGTACACGTTCGGATCGGGGACCAAGCTGGAAATAAAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ2*03_15" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 39, "j_codon_frame": 3, "j_cdr3_end": 9, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null }, { "allele_description_id": "OGRDB:A02503", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-AR7L.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-AR7L*00", "sequence": "TGTATACGTTCGGATCGGGGACCAAGCTGGAAATGAAAC", "coding_sequence": "TGTATACGTTCGGATCGGGGACCAAGCTGGAAATGAAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ2*02" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 39, "j_codon_frame": 3, "j_cdr3_end": 9, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null }, { "allele_description_id": "OGRDB:A02504", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-HVOR.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-HVOR*00", "sequence": "TGTATACGTTCGGATCGGGGACCAAGCTGGAAATAAAAC", "coding_sequence": "TGTATACGTTCGGATCGGGGACCAAGCTGGAAATAAAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ2*03" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 39, "j_codon_frame": 3, "j_cdr3_end": 9, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null }, { "allele_description_id": "OGRDB:A02505", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-IIHF.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-IIHF*00", "sequence": "AATCACATTCAGTGATGGGACCAGACTGGAAATAAAAC", "coding_sequence": "AATCACATTCAGTGATGGGACCAGACTGGAAATAAAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ3*01" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 38, "j_codon_frame": 2, "j_cdr3_end": 8, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": "missing canonical GxG motif and not observed in repertoires in Koe et al.\r\n\r\naatc aca ttc agt gat ggg acc aga ctg gaa ata aaa \r\n I T F S D G T R L E I K \r\n", "curational_tags": [ null ] }, { "allele_description_id": "OGRDB:A02508", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-LUDL.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-LUDL*00", "sequence": "ATTCACGTTCGGCACGGGGACAAAATTGGAAATAAAAC", "coding_sequence": "ATTCACGTTCGGCACGGGGACAAAATTGGAAATAAAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ4*02" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 38, "j_codon_frame": 2, "j_cdr3_end": 8, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null }, { "allele_description_id": "OGRDB:A02502", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-MXRV.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-MXRV*00", "sequence": "TGTACACGTTCGGAGGGGGGACCAAGCTGGAAATAAAAC", "coding_sequence": "TGTACACGTTCGGAGGGGGGACCAAGCTGGAAATAAAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ2*01" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 39, "j_codon_frame": 3, "j_cdr3_end": 9, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null }, { "allele_description_id": "OGRDB:A02509", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-O4CL.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-O4CL*00", "sequence": "GCTCACGTTCGGTGCTGGGACCAAGCTGGAGCTGAAAC", "coding_sequence": "GCTCACGTTCGGTGCTGGGACCAAGCTGGAGCTGAAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ5*01" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 38, "j_codon_frame": 2, "j_cdr3_end": 8, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null }, { "allele_description_id": "OGRDB:A02501", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-WRAP.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-WRAP*00", "sequence": "CCGACGTTCGGTGGAGGCACCAAGCTGGAAATCAATC", "coding_sequence": "CCGACGTTCGGTGGAGGCACCAAGCTGGAAATCAATC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ1*02" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 37, "j_codon_frame": 1, "j_cdr3_end": 7, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null }, { "allele_description_id": "OGRDB:A02507", "allele_description_ref": "OGRDB:Mus musculus:IGKJ-Z5J4.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "31-May-2022", "release_description": "First release", "label": "IGKJ0-Z5J4*00", "sequence": "ATTCACGTTCGGCTCGGGGACAAAGTTGGAAATAAAAC", "coding_sequence": "ATTCACGTTCGGCTCGGGGACAAAGTTGGAAATAAAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGKJ4*01" ], "locus": "IGK", "chromosome": null, "sequence_type": "J", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": null, "species_subgroup_type": null, "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 38, "j_codon_frame": 2, "j_cdr3_end": 8, "j_rs_start": null, "j_rs_end": null, "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null } ], "curation": "IGKJ genes for use with all strains\r\n\r\nAs published in Kos et al. (2022) (in preparation)" } ] }