{ "GermlineSet": [ { "germline_set_id": "OGRDB:G00009", "author": "Justin Kos", "lab_name": "University of Louisville School of Medicine", "lab_address": "University of Louisville, Louisville, KY 40202, USA", "acknowledgements": null, "release_version": 1, "release_description": "IGLV sequences as described in Kos et al. (2022)", "release_date": "2022-05-03", "germline_set_name": "AKR/J IGLV", "germline_set_ref": "OGRDB:AKR/J IGLV.1", "pub_ids": null, "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": "AKR/J", "species_subgroup_type": "strain", "locus": "IGL", "allele_descriptions": [ { "allele_description_id": "OGRDB:A00377", "allele_description_ref": "OGRDB:Mus musculus/AKR/J_IGL:IGLV-53OK.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "03-May-2022", "release_description": "This version as published in preprint at https://www.biorxiv.org/content/10.1101/2022.05.01.489089v1", "label": "IGLV0-53OK*00", "sequence": "CAGGCTGTTGTGACTCAGGAATCTGCACTCACCACATCACCTGGTGGAACAGTCATACTCACTTGTCGCTCAAGTACTGGGGCTGTTACAACTAGTAACTATGCCAACTGGGTCCAAGAAAAACCAGATCATTTATTCACTGGTCTAATAGGTGGTACCAGCAACCGAGCTCCAGGTGTTCCTGTCAGATTCTCAGGCTCCCTGATTGGAGACAAGGCTGCCCTCACCATCACAGGGGCACAGACTGAGGATGATGCAATGTATTTCTGTGCTCTATGGTACAGCACCCATTTC", "coding_sequence": "CAGGCTGTTGTGACTCAGGAATCTGCACTCACCACATCACCTGGTGGAACAGTCATACTCACTTGTCGCTCAAGTACTGGGGCTGTTACAACTAGTAACTATGCCAACTGGGTCCAAGAAAAACCAGATCATTTATTCACTGGTCTAATAGGTGGTACCAGCAACCGAGCTCCAGGTGTTCCTGTCAGATTCTCAGGCTCCCTGATTGGAGACAAGGCTGCCCTCACCATCACAGGGGCACAGACTGAGGATGATGCAATGTATTTCTGTGCTCTATGGTACAGCACCCATTTC", "ext_3prime": null, "aliases": [ "Kos et al: IGLV2*02_AKR" ], "locus": "IGL", "chromosome": null, "sequence_type": "V", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": "AKR/J", "species_subgroup_type": "strain", "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 294, "utr_5_prime_start": null, "utr_5_prime_end": null, "leader_1_start": null, "leader_1_end": null, "leader_2_start": null, "leader_2_end": null, "v_rs_start": null, "v_rs_end": null, "v_gene_delineations": [ { "sequence_delineation_id": "1", "delineation_scheme": "IMGT", "unaligned_sequence": "CAGGCTGTTGTGACTCAGGAATCTGCACTCACCACATCACCTGGTGGAACAGTCATACTCACTTGTCGCTCAAGTACTGGGGCTGTTACAACTAGTAACTATGCCAACTGGGTCCAAGAAAAACCAGATCATTTATTCACTGGTCTAATAGGTGGTACCAGCAACCGAGCTCCAGGTGTTCCTGTCAGATTCTCAGGCTCCCTGATTGGAGACAAGGCTGCCCTCACCATCACAGGGGCACAGACTGAGGATGATGCAATGTATTTCTGTGCTCTATGGTACAGCACCCATTTC", "aligned_sequence": "CAGGCTGTTGTGACTCAGGAATCTGCA...CTCACCACATCACCTGGTGGAACAGTCATACTCACTTGTCGCTCAAGTACTGGGGCTGTTACA.........ACTAGTAACTATGCCAACTGGGTCCAAGAAAAACCAGATCATTTATTCACTGGTCTAATAGGTGGTACC.....................AGCAACCGAGCTCCAGGTGTTCCT...GTCAGATTCTCAGGCTCCCTG......ATTGGAGACAAGGCTGCCCTCACCATCACAGGGGCACAGACTGAGGATGATGCAATGTATTTCTGTGCTCTATGGTACAGCACCCATTTC", "fwr1_start": 1, "fwr1_end": 75, "cdr1_start": 76, "cdr1_end": 102, "fwr2_start": 103, "fwr2_end": 153, "cdr2_start": 154, "cdr2_end": 162, "fwr3_start": 163, "fwr3_end": 270, "cdr3_start": 271, "alignment_labels": [ "1", "2", "3", "4", "5", "6", "7", "8", "9", "10", "11", "12", "13", "14", "15", "16", "17", "18", "19", "20", "21", "22", "23", "24", "25", "26", "27", "28", "29", "30", "31", "32", "33", "34", "35", "36", "37", "38", "39", "40", "41", "42", "43", "44", "45", "46", "47", "48", "49", "50", "51", "52", "53", "54", "55", "56", "57", "58", "59", "60", "61", "62", "63", "64", "65", "66", "67", "68", "69", "70", "71", "72", "73", "74", "75", "76", "77", "78", "79", "80", "81", "82", "83", "84", "85", "86", "87", "88", "89", "90", "91", "92", "93", "94", "95", "96", "97", "98", "99", "100", "101", "102", "103", "104" ] } ], "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null }, { "allele_description_id": "OGRDB:A00378", "allele_description_ref": "OGRDB:Mus musculus/AKR/J_IGL:IGLV-OC5B.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "03-May-2022", "release_description": "This version as published in preprint at https://www.biorxiv.org/content/10.1101/2022.05.01.489089v1", "label": "IGLV0-OC5B*00", "sequence": "CAACTTGTGCTCACTCAGTCATCTTCAGCCTCTTTCTCCCTGGGAGCCTCAGCAAAACTCACGTGCACCTTGAGTAGTCAGCACAGTACGTACACCATTGAATGGTATCAGCAACAGCCACTCAAGCCTCCTAAGTATGTGATGGAGCTTAAGAAAGATGGAAGCCACAGCACAGGTGATGGGATTCCTGATCGCTTCTCTGGATCCAGCTCTGGTGCTGATCGCTACCTTAGCATTTCCAACATCCAGCCTGAAGATGAAGCAATATACATCTGTGGTGTGGGTGATACAATTAAGGAACAATTTGTGTAAC", "coding_sequence": "CAACTTGTGCTCACTCAGTCATCTTCAGCCTCTTTCTCCCTGGGAGCCTCAGCAAAACTCACGTGCACCTTGAGTAGTCAGCACAGTACGTACACCATTGAATGGTATCAGCAACAGCCACTCAAGCCTCCTAAGTATGTGATGGAGCTTAAGAAAGATGGAAGCCACAGCACAGGTGATGGGATTCCTGATCGCTTCTCTGGATCCAGCTCTGGTGCTGATCGCTACCTTAGCATTTCCAACATCCAGCCTGAAGATGAAGCAATATACATCTGTGGTGTGGGTGATACAATTAAGGAACAATTTGTGTAAC", "ext_3prime": null, "aliases": [ "Kos et al: IGLV3*01_AKR" ], "locus": "IGL", "chromosome": null, "sequence_type": "V", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": "AKR/J", "species_subgroup_type": "strain", "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 313, "utr_5_prime_start": null, "utr_5_prime_end": null, "leader_1_start": null, "leader_1_end": null, "leader_2_start": null, "leader_2_end": null, "v_rs_start": null, "v_rs_end": null, "v_gene_delineations": [ { "sequence_delineation_id": "1", "delineation_scheme": "IMGT", "unaligned_sequence": "CAACTTGTGCTCACTCAGTCATCTTCAGCCTCTTTCTCCCTGGGAGCCTCAGCAAAACTCACGTGCACCTTGAGTAGTCAGCACAGTACGTACACCATTGAATGGTATCAGCAACAGCCACTCAAGCCTCCTAAGTATGTGATGGAGCTTAAGAAAGATGGAAGCCACAGCACAGGTGATGGGATTCCTGATCGCTTCTCTGGATCCAGCTCTGGTGCTGATCGCTACCTTAGCATTTCCAACATCCAGCCTGAAGATGAAGCAATATACATCTGTGGTGTGGGTGATACAATTAAGGAACAATTTGTGTAAC", "aligned_sequence": "CAACTTGTGCTCACTCAGTCATCTTCA...GCCTCTTTCTCCCTGGGAGCCTCAGCAAAACTCACGTGCACCTTGAGTAGTCAGCACAGT...............ACGTACACCATTGAATGGTATCAGCAACAGCCACTCAAGCCTCCTAAGTATGTGATGGAGCTTAAGAAAGAT.........GGAAGCCACAGCACAGGTGATGGGATTCCT...GATCGCTTCTCTGGATCCAGC......TCTGGTGCTGATCGCTACCTTAGCATTTCCAACATCCAGCCTGAAGATGAAGCAATATACATCTGTGGTGTGGGTGATACAATTAAGGAACAATTTGTGTAAC", "fwr1_start": 1, "fwr1_end": 75, "cdr1_start": 76, "cdr1_end": 96, "fwr2_start": 97, "fwr2_end": 147, "cdr2_start": 148, "cdr2_end": 168, "fwr3_start": 169, "fwr3_end": 276, "cdr3_start": 277, "alignment_labels": [ "1", "2", "3", "4", "5", "6", "7", "8", "9", "10", "11", "12", "13", "14", "15", "16", "17", "18", "19", "20", "21", "22", "23", "24", "25", "26", "27", "28", "29", "30", "31", "32", "33", "34", "35", "36", "37", "38", "39", "40", "41", "42", "43", "44", "45", "46", "47", "48", "49", "50", "51", "52", "53", "54", "55", "56", "57", "58", "59", "60", "61", "62", "63", "64", "65", "66", "67", "68", "69", "70", "71", "72", "73", "74", "75", "76", "77", "78", "79", "80", "81", "82", "83", "84", "85", "86", "87", "88", "89", "90", "91", "92", "93", "94", "95", "96", "97", "98", "99", "100", "101", "102", "103", "104" ] } ], "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null }, { "allele_description_id": "OGRDB:A00376", "allele_description_ref": "OGRDB:Mus musculus/AKR/J_IGL:IGLV-QG74.1", "maintainer": "William Lees", "acknowledgements": null, "lab_address": "Birkbeck College, University of London, Malet Street, London", "release_version": 1, "release_date": "03-May-2022", "release_description": "This version as published in preprint at https://www.biorxiv.org/content/10.1101/2022.05.01.489089v1", "label": "IGLV0-QG74*00", "sequence": "CAGGCTGTTGTGACTCAGGAATCTGCACTCACCACATCACCTGGTGAAACAGTCACACTCACTTGTCGCTCAAGTACTGGGGCTGTTACAACTAGTAACTATGCCAACTGGGTCCAAGAAAAACCAGATCATTTATTCACTGGTCTAATAGGTGGTACCAACAACCGAGCTCCAGGTGTTCCTGCCAGATTCTCAGGCTCCCTGATTGGAGACAAGGCTGCCCTCACCATCACAGGGGCACAGACTGAGGATGAGGCAATATATTTCTGTGCTCTATGGTACAGCAACCATTTC", "coding_sequence": "CAGGCTGTTGTGACTCAGGAATCTGCACTCACCACATCACCTGGTGAAACAGTCACACTCACTTGTCGCTCAAGTACTGGGGCTGTTACAACTAGTAACTATGCCAACTGGGTCCAAGAAAAACCAGATCATTTATTCACTGGTCTAATAGGTGGTACCAACAACCGAGCTCCAGGTGTTCCTGCCAGATTCTCAGGCTCCCTGATTGGAGACAAGGCTGCCCTCACCATCACAGGGGCACAGACTGAGGATGAGGCAATATATTTCTGTGCTCTATGGTACAGCAACCATTTC", "ext_3prime": null, "aliases": [ "Kos et al: IGLV1*01_AKR" ], "locus": "IGL", "chromosome": null, "sequence_type": "V", "functional": true, "inference_type": "Rearranged only", "species": { "id": "NCBITAXON:10090", "label": "Mus musculus" }, "species_subgroup": "AKR/J", "species_subgroup_type": "strain", "status": null, "gene_designation": null, "subgroup_designation": null, "allele_designation": null, "allele_similarity_cluster_designation": null, "allele_similarity_cluster_member_id": null, "gene_start": 1, "gene_end": 294, "utr_5_prime_start": null, "utr_5_prime_end": null, "leader_1_start": null, "leader_1_end": null, "leader_2_start": null, "leader_2_end": null, "v_rs_start": null, "v_rs_end": null, "v_gene_delineations": [ { "sequence_delineation_id": "1", "delineation_scheme": "IMGT", "unaligned_sequence": "CAGGCTGTTGTGACTCAGGAATCTGCACTCACCACATCACCTGGTGAAACAGTCACACTCACTTGTCGCTCAAGTACTGGGGCTGTTACAACTAGTAACTATGCCAACTGGGTCCAAGAAAAACCAGATCATTTATTCACTGGTCTAATAGGTGGTACCAACAACCGAGCTCCAGGTGTTCCTGCCAGATTCTCAGGCTCCCTGATTGGAGACAAGGCTGCCCTCACCATCACAGGGGCACAGACTGAGGATGAGGCAATATATTTCTGTGCTCTATGGTACAGCAACCATTTC", "aligned_sequence": "CAGGCTGTTGTGACTCAGGAATCTGCA...CTCACCACATCACCTGGTGAAACAGTCACACTCACTTGTCGCTCAAGTACTGGGGCTGTTACA.........ACTAGTAACTATGCCAACTGGGTCCAAGAAAAACCAGATCATTTATTCACTGGTCTAATAGGTGGTACC.....................AACAACCGAGCTCCAGGTGTTCCT...GCCAGATTCTCAGGCTCCCTG......ATTGGAGACAAGGCTGCCCTCACCATCACAGGGGCACAGACTGAGGATGAGGCAATATATTTCTGTGCTCTATGGTACAGCAACCATTTC", "fwr1_start": 1, "fwr1_end": 75, "cdr1_start": 76, "cdr1_end": 102, "fwr2_start": 103, "fwr2_end": 153, "cdr2_start": 154, "cdr2_end": 162, "fwr3_start": 163, "fwr3_end": 270, "cdr3_start": 271, "alignment_labels": [ "1", "2", "3", "4", "5", "6", "7", "8", "9", "10", "11", "12", "13", "14", "15", "16", "17", "18", "19", "20", "21", "22", "23", "24", "25", "26", "27", "28", "29", "30", "31", "32", "33", "34", "35", "36", "37", "38", "39", "40", "41", "42", "43", "44", "45", "46", "47", "48", "49", "50", "51", "52", "53", "54", "55", "56", "57", "58", "59", "60", "61", "62", "63", "64", "65", "66", "67", "68", "69", "70", "71", "72", "73", "74", "75", "76", "77", "78", "79", "80", "81", "82", "83", "84", "85", "86", "87", "88", "89", "90", "91", "92", "93", "94", "95", "96", "97", "98", "99", "100", "101", "102", "103", "104" ] } ], "unrearranged_support": [], "rearranged_support": [], "paralogs": null, "curation": null, "curational_tags": null } ], "curation": "The germline set is based on sequences published in Kos et al. (2022) (in preparation)" } ] }